中华肝胆外科杂志
中華肝膽外科雜誌
중화간담외과잡지
CHINESE JOURNAL OF HEPATOBILIARY SURGERY
2010年
11期
845-847
,共3页
范作升%孙仕林%李杰%邱昌城%赵宏伟%高涛%王升%张波%李开富%张言敏
範作升%孫仕林%李傑%邱昌城%趙宏偉%高濤%王升%張波%李開富%張言敏
범작승%손사림%리걸%구창성%조굉위%고도%왕승%장파%리개부%장언민
胆肠吻合术%支撑管%实验研究
膽腸吻閤術%支撐管%實驗研究
담장문합술%지탱관%실험연구
Cholecystojejunostomy%Support tube%Experimental study
目的 研究支撑引流管在胆肠吻合中的置放反应及其病理改变.方法 将8头实验猪随机分为两组,分别实施置管与不置管的胆肠和胆管吻合各2头.喂养3个月后宰杀取标本做病理对照检验.结果 置管组大体解剖显示吻合口炎性增生、管壁硬化增生、管腔挛缩狭窄、有结石形成;病理切片镜下显示胆管黏膜间质中淋巴细胞、浆细胞等慢性炎性细胞浸润,黏膜下大量纤维组织增生.未置管组大体解剖和病理切片仅见轻微炎性改变,且无管腔狭窄.结论 放在体内的异物支撑引流管,不仅不能防止狭窄形成,反而可刺激促进炎性增生、组织硬化和管腔狭窄形成.
目的 研究支撐引流管在膽腸吻閤中的置放反應及其病理改變.方法 將8頭實驗豬隨機分為兩組,分彆實施置管與不置管的膽腸和膽管吻閤各2頭.餵養3箇月後宰殺取標本做病理對照檢驗.結果 置管組大體解剖顯示吻閤口炎性增生、管壁硬化增生、管腔攣縮狹窄、有結石形成;病理切片鏡下顯示膽管黏膜間質中淋巴細胞、漿細胞等慢性炎性細胞浸潤,黏膜下大量纖維組織增生.未置管組大體解剖和病理切片僅見輕微炎性改變,且無管腔狹窄.結論 放在體內的異物支撐引流管,不僅不能防止狹窄形成,反而可刺激促進炎性增生、組織硬化和管腔狹窄形成.
목적 연구지탱인류관재담장문합중적치방반응급기병리개변.방법 장8두실험저수궤분위량조,분별실시치관여불치관적담장화담관문합각2두.위양3개월후재살취표본주병리대조검험.결과 치관조대체해부현시문합구염성증생、관벽경화증생、관강련축협착、유결석형성;병리절편경하현시담관점막간질중림파세포、장세포등만성염성세포침윤,점막하대량섬유조직증생.미치관조대체해부화병리절편부견경미염성개변,차무관강협착.결론 방재체내적이물지탱인류관,불부불능방지협착형성,반이가자격촉진염성증생、조직경화화관강협착형성.
Objective To investigate the place reaction of support drainage tube in cholecystojejunostomy and its pathological changes.Methods Eight pigs were randomized into 2 groups.The tube-placing cholecystojeunostomy(n=2)or choledochocholedochostomy(n=2)and non-tube-placing cholecystojejunostomy(n=2)or choledochocholedochostomy(n=2)were performed respectively.All the 8 pigs were sarcrificed 3 months after the operation for pathological examination.Results Gross anatomy catheter group showed anastomotic inflammatory hyperplasia, wall hardening hyperplasia,luminal narrow contracture and stone formation.Microscopic biopsy showed bile duct mucosa in interstitial lymphocytes, plasma cells and other chronic inflammatory cell infiltration, a large number of fibrous tissue hyperplasia.However, these features were not found in pigs without placing the tube.Conclusion The tube can not prevent the stenosis.It might promote the formation of stricture since it can stimulate inflammatory hyperplasia and tissue hardening.
