HIV耐药性及检测方法最新进展
HIV내약성급검측방법최신진전
New development of methods in HIV drug resistance study
  • 万方数据
    国际生物医学工程杂志 국제생물의학공정잡지
    INTERNATIONAL JOURNAL OF BIOMEDICAL ENGINEERING
    2012年 4期 247-250,253,后插5 ,共6页

    韩卫宁%高勇

    한위저%고용

    耐药突变%基因型耐药检测%表型耐药检测%酵母重组克隆技术 耐藥突變%基因型耐藥檢測%錶型耐藥檢測%酵母重組剋隆技術
    내약돌변%기인형내약검측%표형내약검측%효모중조극륭기술
    Drug resistance mutations%Genotypic drug susceptibility assay%Phenotypic drug susceptibility assay%Yeast-based recombination method
    人类免疫缺陷病毒(HIV)基因组发生耐药突变导致的耐药性是抗病毒治疗失败的最主要原因.查明艾滋病患者体内耐药准种的变化并及时发现新的耐药突变位点,对于指导有效临床用药和研发新的抗病毒药物都有重要意义.HIV耐药检测主要分为基因型检测和表型检测.对这一领域的最新进展进行综述.
    인류면역결함병독(HIV)기인조발생내약돌변도치적내약성시항병독치료실패적최주요원인.사명애자병환자체내내약준충적변화병급시발현신적내약돌변위점,대우지도유효림상용약화연발신적항병독약물도유중요의의.HIV내약검측주요분위기인형검측화표형검측.대저일영역적최신진전진행종술.
    The emergence of drug resistance mutations in human immunodeficiency virus (HIV) genome is the major reason for antiviral treatments failure.To investigate the drug-resistance viral quasispecies in HIV-infected individuals and to find out the new drug resistance mutations have significant effects on directing effective clinical treatment and developing novel antiviral drugs.HIV drug resistance tests mainly include genotypic drug susceptibility assay and phenotypic drug susceptibility assay.We reviewed in this article some novel development in the field.
    원문보기 원문다운로드 사이트로이동
저자의 최근 논문