CAJ | 학술논문

化疗是肿瘤综合治疗的主要方式之一,多年来在肿瘤治疗中发挥着重要作用.但近年来低剂量化疗以其利用化疗药物的新靶点、采取合理的给药方式和计划,且相对于最大耐受量化疗具有毒副反应小、患者耐受性明显提高、疗效更佳等优势,已逐渐成为肺癌治疗研究的热点和新策略.本文就低剂量化疗的起源、作用机制、优势及存在问题等方面的研究进展作一综述.
화료시종류종합치료적주요방식지일,다년래재종류치료중발휘착중요작용.단근년래저제양화료이기이용화료약물적신파점、채취합리적급약방식화계화,차상대우최대내수양화료구유독부반응소、환자내수성명현제고、료효경가등우세,이축점성위폐암치료연구적열점화신책략.본문취저제양화료적기원、작용궤제、우세급존재문제등방면적연구진전작일종술.
Chemotherapy is one of the main ways of comprehensive treatment of tumor,and it has played an important role in the treatment of tumor for many years. In recent years, low-dose chemotherapy has been a hot research and new strategy in the treatment of lung cancer, because it uses new target of chemotherapy drugs,takes reasonable manner of administration and plan,and has fewer toxic side effects, higher patient tolerance and better therapeutic effect compared with the maximum tolerated dose chemotherapy. This article reviews the research progress on the origin, mechanism, predominance and problems of low-dose chemotherapy.