CAJ | 학술논문

乳腺癌是一种异质性肿瘤,代谢异常在乳腺癌的发生、发展中起重要作用.n-3多不饱和脂肪酸(PUFA)可以通过多种途径改变乳腺癌细胞的脂肪酸代谢,调节癌基因和抑癌基因的表达,从而在乳腺癌的化疗、放疗、内分泌治疗和分子靶向治疗等综合治疗中起作用.
유선암시일충이질성종류,대사이상재유선암적발생、발전중기중요작용.n-3다불포화지방산(PUFA)가이통과다충도경개변유선암세포적지방산대사,조절암기인화억암기인적표체,종이재유선암적화료、방료、내분비치료화분자파향치료등종합치료중기작용.
Breast cancer is a type of heterogenetic neoplasm.Metabolic dysfunction plays a pivotal role in the pathogenesis and progress of breast cancer.N-3 polyunsaturated fatty acid (PUFA) could change fatty acid metabolism of breast cancer cells and modulate expression of oncogenes and anti-oncogenes through various ways.It may provide therapeutic opportunities in the treatment of chemotherapy,radiotherapy,endocrine therapy and molecule targeted therapy of breast cancer.