CAJ | 학술논문

背景非去极化肌松药在临床麻醉中使用非常普遍，术后不可避免地发生肌松残余作用，其危害主要为呼吸不良事件，严重可导致死亡。目的有效合理的肌松拮抗能降低术后肌松残余的发生率，减少相关并发症，因此，拮抗至关重要。内容阐述非去极化肌松药使用后手术结束时是否需要拮抗、拮抗的时机、拮抗剂的剂量和新的拮抗模式。趋向选择性肌松拮抗可极大地降低，甚至可能避免术后肌松残余作用的发生，将成为未来主要的拮抗模式。
배경비거겁화기송약재림상마취중사용비상보편，술후불가피면지발생기송잔여작용，기위해주요위호흡불량사건，엄중가도치사망。 목적유효합리적기송길항능강저술후기송잔여적발생솔，감소상관병발증，인차，길항지관중요。내용천술비거겁화기송약사용후수술결속시시부수요길항、길항적시궤、길항제적제량화신적길항모식。추향선택성기송길항가겁대지강저，심지가능피면술후기송잔여작용적발생，장성위미래주요적길항모식。
Background Currently, non-depolarizing neuromuscular relaxant have been widely used in anesthesia for many surgical procedures. After administrating the relaxant, postoperative residual neuromuscular blockage (RNMB) ensues inevitably and mainly results in adverse respiratory events or even death occasionally. Objective Adequate reversal of neuromuscular blockage is crucial to decrease the incidence of postoperative RNMB and contribute to reduce the related complications. Content This article is aimed to review the updates on optimal neuromuscular management strategies, including the necessity of postoperative anticholinesterase agents, the most appropriate reversal opportunity and dose, as well as the new mode of selective reversal of RNMB.Trend The selective reversal of RNMB will reduce the occurrence of postoperative RNMB dramatically, and possibly even avoid RNMB. The novel preventing mode will lead the mainstream of preventing postoperative RNMB.