CAJ | 학술논문

目的探讨米索前列醇用于足月妊娠促宫颈成熟和引产的有效性及安全性.方法选择2007年7月至2009年7月在我院住院的初产妇67例作为试验组,选择同期相同条件的足月孕妇51例作为对照组,试验组用米索前列醇引产,对照组用催产素静脉滴注引产.比较2组产妇宫颈成熟度评分、临产时间、破膜时间、分娩时间、总产程时间、分娩情况和结局以及新生儿评分.结果试验组用于足月妊娠促宫颈成熟和引产效果明显优于对照组(有效率为92.5%比80.4%,P＜0.01),用药至临产时间明显短于对照组[(41.31±17.25)min比(57.14±14.72)min,P＜0.01],对母婴影响无明显差别.试验组患者最终经阴道顺娩48例,阴道助娩4例,剖宫产15例,对照组阴道顺娩32例,阴道助娩3例,剖宫产16例.结论米索前列醇是一种安全有效方便实惠的引产药物,对母婴没有明显不良影响,可在临床上应用.
목적 탐토미색전렬순용우족월임신촉궁경성숙화인산적유효성급안전성.방법 선택2007년7월지2009년7월재아원주원적초산부67례작위시험조,선택동기상동조건적족월잉부51례작위대조조,시험조용미색전렬순인산,대조조용최산소정맥적주인산.비교2조산부궁경성숙도평분、임산시간、파막시간、분면시간、총산정시간、분면정황화결국이급신생인평분.결과 시험조용우족월임신촉궁경성숙화인산효과명현우우대조조(유효솔위92.5%비80.4%,P＜0.01),용약지임산시간명현단우대조조[(41.31±17.25)min비(57.14±14.72)min,P＜0.01],대모영영향무명현차별.시험조환자최종경음도순면48례,음도조면4례,부궁산15례,대조조음도순면32례,음도조면3례,부궁산16례.결론 미색전렬순시일충안전유효방편실혜적인산약물,대모영몰유명현불량영향,가재림상상응용.
Objective To investigate the efficacy and safety of misoprostol in term pregnancy for cervical ripening and induction of labor. Methods Sixty-seven term primipara were treated from July 2007 to July 2009 (test group) ,and 51 term primipara with same conditions were conducted in the control group during the same period. Misoprostol was used in the test group and oxytoxin was used in the control group. The differences of bishop cervical score, time of labor, total stage of labor, condition and results in deliveryin and baby apgar score were observed. Results Misoprostol used in the test group showed a shorter time of labor than oxytoxin used in the control group( P ＜ 0.01 ). The mission success rate in the test group was higher than that in the control group. Conclusions Misoprostol is a safe and effective new drug used for cervical ripening and induction of labor.