CAJ | 학술논문

目的观察氯诺昔康用于鼻内镜手术后患者自控静脉镇痛(PCIA)的临床效果和安全性.方法 74例拟行全身麻醉下鼻内镜手术患者完全随机分为试验组和对照组,每组37例.试验组予氯诺昔康行PCIA,对照组予芬太尼行PCIA.分别记录2组患者术后2、4、8、24、32 h的疼痛视觉模拟评分(VAS)、警觉/镇静评分(OAA/S)和血氧饱和度(spO2),并记录PCIA期间2组患者不良反应发生率.结果手术后各时间点2组患者VhS评分均在3分以下,组间差异无统计学意义,P>0.05.各时间点OAA/S评分和spO2,试验组均高于对照组,P<0.05.试验组不良反应总发生率13.5%(5例)显著低于对照组45.9%(17例),P<0.05.结论氯诺昔康用于鼻内镜手术后PCIA镇痛效果确切,对患者意识水平和呼吸影响小,不良反应发生率低.
목적 관찰록낙석강용우비내경수술후환자자공정맥진통(PCIA)적림상효과화안전성.방법 74례의행전신마취하비내경수술환자완전수궤분위시험조화대조조,매조37례.시험조여록낙석강행PCIA,대조조여분태니행PCIA.분별기록2조환자술후2、4、8、24、32 h적동통시각모의평분(VAS)、경각/진정평분(OAA/S)화혈양포화도(spO2),병기록PCIA기간2조환자불량반응발생솔.결과 수술후각시간점2조환자VhS평분균재3분이하,조간차이무통계학의의,P>0.05.각시간점OAA/S평분화spO2,시험조균고우대조조,P<0.05.시험조불량반응총발생솔13.5%(5례)현저저우대조조45.9%(17례),P<0.05.결론 록낙석강용우비내경수술후PCIA진통효과학절,대환자의식수평화호흡영향소,불량반응발생솔저.
Objective To evaluate the clinic efficacy and safety of lornoxicam for patient controlled intravenous analgesia after functional endoscopic sinus surgery. Methods Seventy-four patients undergoing functional endoscopic sinus surgery under general anesthesia were randomly divided into experimental group and control group, with 37 cases in each group. Lornoxicam was administered in experimental group and fentanyl was applied in control group. The visual analogue scale (VAS) score, OAA/S(observer assessment alertness/sedation) score and SpO2 were recorded at 2, 4, 8, 24 and 32 hours after the operation respectively. The adverse reactions were also recorded. Results The VAS scores at each timepoint in both groups were all not more than 3 and there was no significantly difference between the two groups (P > 0.05 ). The OAA/S score and SpO2 in each timepoint were higher in experimental group than those in control groups (P < 0.05 ). The incidence of adverse reactions was significandy lower in experimental group than that in control group (P <0.05). Conclusion Patient controlled intravenous analgesia (PCI A) with lornoxicam can provide efficient and safe postoperative analgesia for patients of functional endoscopic sinus surgery relatively with few influence on the level of consciousness and respiration.