CAJ | 학술논문

目的研究广州市中老年人大豆异黄酮摄入与血脂的关系.方法用食物频数问卷分析395名40～65岁广州市居民每日大豆异黄酮及其他食物和营养素的摄入量,抽取空腹静脉血测定血脂.结果 134名男性和261名女性的大豆异黄酮摄入分别为11.95(0～61.96)mg/d和14.90(0～82.52)mg/d.按照大豆异黄酮摄入量将研究对象等分为低、中、高三组,在校正了总能量摄入和脂肪供能比后,三组间TC、LDL-C差异有统计学意义(P值分别为0.002、0.008),并存在剂量效应关系(趋势分析P值分别为<0.001、0.012);高摄入组与低摄入组相比,TC、LDL-C分别下降7.06%、10.13%.在进一步校正年龄、BMI和腰臀比后,上述结果无明显改变.结论膳食大豆异黄酮摄入与血浆TC、LDL-C负相关.
목적 연구엄주시중노년인대두이황동섭입여혈지적관계.방법 용식물빈수문권분석395명40～65세엄주시거민매일대두이황동급기타식물화영양소적섭입량,추취공복정맥혈측정혈지.결과 134명남성화261명녀성적대두이황동섭입분별위11.95(0～61.96)mg/d화14.90(0～82.52)mg/d.안조대두이황동섭입량장연구대상등분위저、중、고삼조,재교정료총능량섭입화지방공능비후,삼조간TC、LDL-C차이유통계학의의(P치분별위0.002、0.008),병존재제량효응관계(추세분석P치분별위<0.001、0.012);고섭입조여저섭입조상비,TC、LDL-C분별하강7.06%、10.13%.재진일보교정년령、BMI화요둔비후,상술결과무명현개변.결론 선식대두이황동섭입여혈장TC、LDL-C부상관.
Objective To study the mlationship between dietary soy isoflavones and blood lipids among residents of 40-65 years old,in Guangzhou.Methods Dietary soy isoflavones and other nutrients intakes were assessed with quantitative food frequency questionnaire(FFQ).Total cholesterol(TC),triglycerides(TG),HDL cholesterol(HDL-C)and LDL cholesterol(LDL-C)in plasma were measured with colorimetry.Results Ranges of dietary soy isoflavones intake among 134 males and 261 females were fxom 0 mg/day to 61.96 mg/day and 0 mg/day to 82.52 mg/day,with means of 11.95 mg/day,14.90 mg/day,respectively.After adjusted for total energy intake and fat percent energy,difiefences of TC,LDL-C in total population and TC in women were statistically significant between groups(P value was 0.002,0.008,0.004,respectively) and dose-effect relationships(P value was <0.001.0.012.0.001,respectively)were observed between dietary soy isoflavones intake and the upper mentioned three indices.Compared with the low-intake group,tbese three indices lowered 7.06%,10.13%and 7.48%,respectively in high-intake group.Critical significance of LDL-C was observed both in women and men between groups.Further controlled for age,BMI and WHR,no obvious change of the results was observed.Conclusion Moderate intakes of soy isoflavone as part of a regular diet seemed to be associated with favorable blood lipid levels.