CAJ | 학술논문

目的探讨神经系统结节病的临床特点及治疗方法.方法对1例经颅脑MRI检查定位下丘脑病变患者,行经纵裂-终板入路部分切除,术后结合激素治疗,病理诊断为结节病,对其病史结合文献进行回顾分析.结果神经系统结节病临床非常罕见,术前诊断困难,多数确诊神经系统结节病的患者都有全身多系统的侵犯,尤其是肺和心脏.明确病理诊断后,激素治疗效果通常满意.结论与神经系统症状或体征相对应的临床病史结合病理活检可以明确神经系统结节病的诊断,早期足量应用激素可作为有效的治疗手段.
목적 탐토신경계통결절병적림상특점급치료방법.방법 대1례경로뇌MRI검사정위하구뇌병변환자,행경종렬-종판입로부분절제,술후결합격소치료,병리진단위결절병,대기병사결합문헌진행회고분석.결과 신경계통결절병림상비상한견,술전진단곤난,다수학진신경계통결절병적환자도유전신다계통적침범,우기시폐화심장.명학병리진단후,격소치료효과통상만의.결론 여신경계통증상혹체정상대응적림상병사결합병리활검가이명학신경계통결절병적진단,조기족량응용격소가작위유효적치료수단.
Objective To study the clinical characters and therapy of the neurosarcoidosis.Methods Combined with review of the literatures,the history and clinical data of a patient suffered from hypothalamus neurosarcoidosis,whose diagnosis was confirmed by MRI,corticotherapy and pathological diagnosis after partial resection via interhemispheric trans - lamina terminalis approach,were analyzed.Results The neurosarcoidosis was very rare.The diagnosis was often difficult before operation.Most patients who suffered neurosarcoidosis had findings suggestive of multisystem disease,particularly lung and cardiac involvement.After pathological diagnosis,the effect of corticotherapy was usually satisfactory.Conclusion The diagnosis of neurosarcoidosis is made by observing an appropriate clinical history with neurologic signs or symptoms,accompanied by findings on the biopsy.The early corticotherapy of full dose was approved to be an effective method.