北方药学
北方藥學
북방약학
JOURNAL OF NORTH PHARMACY
2013年
8期
20-20,21
,共2页
喜炎平注射液%不良反应
喜炎平註射液%不良反應
희염평주사액%불량반응
Xiyanping Injection%Adverse reaction
目的:探讨使用喜炎平注射液后发生不良反应的特点及规律。方法:对11例使用喜炎平注射液后出现不良反应的患者的基本情况、原发疾病、不良反应发生情况进行分析。结果:喜炎平注射液所致11例不良反应患者女性较男性稍多,但没有统计学差异(P>0.05);不良反应患者中15岁以下的占8例,与其余年龄段相比,具有统计学差异(P<0.05);11例患者原发病均属于感染性疾病;不良反应出现在15~45min者占8例,与<15min组相比差异具有统计学意义(P<0.05);不良反应临床表现为全身反应(6例),皮肤及附件损害(3例),心血管系统损害(2例)。结论:喜炎平注射液致不良反应与患者性别无明显关系,不良反应多发生在15岁以下患者中,不良反应时间多出现在用药后30min左右,不良反应多表现为全身反应、皮肤及附件损害及心血管系统损害。
目的:探討使用喜炎平註射液後髮生不良反應的特點及規律。方法:對11例使用喜炎平註射液後齣現不良反應的患者的基本情況、原髮疾病、不良反應髮生情況進行分析。結果:喜炎平註射液所緻11例不良反應患者女性較男性稍多,但沒有統計學差異(P>0.05);不良反應患者中15歲以下的佔8例,與其餘年齡段相比,具有統計學差異(P<0.05);11例患者原髮病均屬于感染性疾病;不良反應齣現在15~45min者佔8例,與<15min組相比差異具有統計學意義(P<0.05);不良反應臨床錶現為全身反應(6例),皮膚及附件損害(3例),心血管繫統損害(2例)。結論:喜炎平註射液緻不良反應與患者性彆無明顯關繫,不良反應多髮生在15歲以下患者中,不良反應時間多齣現在用藥後30min左右,不良反應多錶現為全身反應、皮膚及附件損害及心血管繫統損害。
목적:탐토사용희염평주사액후발생불량반응적특점급규률。방법:대11례사용희염평주사액후출현불량반응적환자적기본정황、원발질병、불량반응발생정황진행분석。결과:희염평주사액소치11례불량반응환자녀성교남성초다,단몰유통계학차이(P>0.05);불량반응환자중15세이하적점8례,여기여년령단상비,구유통계학차이(P<0.05);11례환자원발병균속우감염성질병;불량반응출현재15~45min자점8례,여<15min조상비차이구유통계학의의(P<0.05);불량반응림상표현위전신반응(6례),피부급부건손해(3례),심혈관계통손해(2례)。결론:희염평주사액치불량반응여환자성별무명현관계,불량반응다발생재15세이하환자중,불량반응시간다출현재용약후30min좌우,불량반응다표현위전신반응、피부급부건손해급심혈관계통손해。
Objective:To explore the rules and causes of adverse reactions by using Xiyanping Injection. Methods:Analysing 11 patients' basic,primary disease,the incidence of adverse reactions who causing adverse drug reactions by Xiyanping Injection. Results:11 cases of Xiyanping injection adverse reactions in patients with women slightly more than men,but there is no statistical significant(P>0.05);Patients under 15 years of age accounted for 8 cases of adverse reactions in patients,the age of 15 to 60 accounted for 3 cases,with statistically significant (P<0.05);11 patients' primary disease are infectious diseases;adverse reactions occur in 15min-45min accounted for 8 cases,compared to<15min group,the difference was statistical significant(P<0.05);clinical manifestations of adverse reactions included the systemic reactions (6 cases),skin and appendages (3 cases),cardiovascular system damage (2 cases). Conclusions:Xiyanping injection adverse reactions caused no significant relationship with patients' gender,adverse reactions mostly occurred in patients under the age of 15,the adverse reaction time more appear in 30min after administration,adverse reactions more performance for the damage to the systemic reactions,skin and its appendages and cardiovascular system damage.