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中华航海医学与高气压医学杂志 중화항해의학여고기압의학잡지
CHINESE JOURNAL OF NAUTICAL MEDICINE AND HYPERBARIC MEDICINE
2009年 4期 207-210 ,共4页

方以群%刘景昌%时粉周%张明月%陈海庭%王瑞淦%李斌%张洪柱%丁江舟

방이군%류경창%시분주%장명월%진해정%왕서감%리빈%장홍주%정강주

高压氧%脑缺血%N-甲基-D-门冬氨酸(NMDA)%海马神经细胞高壓氧%腦缺血%N-甲基-D-門鼕氨痠(NMDA)%海馬神經細胞
고압양%뇌결혈%N-갑기-D-문동안산(NMDA)%해마신경세포
Hyperbaric oxygen%Cerebral ischemia%N-methal-D-aspartate%Hippocampus

显,但显著高于假手术组(P<0.01).结论脑缺血后,海马区神经细胞NMDA受体的Bmax显著增加,氯胺酮、氯胺酮+高压氧治疗可使Bmax降低.可能通过此途径减少细胞外Ca2+内流,恢复细胞内游离Ca2+浓度,从而起到高压氧治疗脑缺血的作用.
현,단현저고우가수술조(P<0.01).결론 뇌결혈후,해마구신경세포NMDA수체적Bmax현저증가,록알동、록알동+고압양치료가사Bmax강저.가능통과차도경감소세포외Ca2+내류,회복세포내유리Ca2+농도,종이기도고압양치료뇌결혈적작용.
x, which might reduce entry of Ca2+ into cells during ischemia and reperfusion, and at the same time, restore concentration of intracellular calcium [Ca2+]. All this might account for the therapeutic effect of HBO on cerebral ischemia.