中华内分泌外科杂志
中華內分泌外科雜誌
중화내분비외과잡지
CHINESE JOURNAL OF ENDOCRINE SURGERY
2011年
6期
377-379
,共3页
陈龙舟%唐静%王亚丽%李青国%邵玮洲%王金星%王凤良%王水
陳龍舟%唐靜%王亞麗%李青國%邵瑋洲%王金星%王鳳良%王水
진룡주%당정%왕아려%리청국%소위주%왕금성%왕봉량%왕수
抗酒石酸酸性磷酸酶5b%乳腺癌%骨转移
抗酒石痠痠性燐痠酶5b%乳腺癌%骨轉移
항주석산산성린산매5b%유선암%골전이
TRACP5b%Breast cancer%Bone metastasis
目的 探讨血清抗酒石酸酸性磷酸酶5b(TRACP5b)预测淋巴结阴性乳腺癌骨转移的临床价值.方法 采用酶联免疫吸附法(ELISA)检测18例健康女性、26例淋巴结阴性乳腺癌的血清TRACP5b水平.结果 乳腺癌组血清TRACP5b水平为(3.85±0.85) U/L较健康组(2.08±0.84) U/L明显升高,差异有统计学意义(P＜0.05)；血清TRACP5b预测淋巴结阴性乳腺癌骨转移的敏感性为42.31％,特异性为94.44％.结论 血清TRACP5b在早期预测乳腺癌骨转移中的敏感性和特异性良好,可作为诊断乳腺癌骨转移的血清标记物之一.
目的 探討血清抗酒石痠痠性燐痠酶5b(TRACP5b)預測淋巴結陰性乳腺癌骨轉移的臨床價值.方法 採用酶聯免疫吸附法(ELISA)檢測18例健康女性、26例淋巴結陰性乳腺癌的血清TRACP5b水平.結果 乳腺癌組血清TRACP5b水平為(3.85±0.85) U/L較健康組(2.08±0.84) U/L明顯升高,差異有統計學意義(P＜0.05)；血清TRACP5b預測淋巴結陰性乳腺癌骨轉移的敏感性為42.31％,特異性為94.44％.結論 血清TRACP5b在早期預測乳腺癌骨轉移中的敏感性和特異性良好,可作為診斷乳腺癌骨轉移的血清標記物之一.
목적 탐토혈청항주석산산성린산매5b(TRACP5b)예측림파결음성유선암골전이적림상개치.방법 채용매련면역흡부법(ELISA)검측18례건강녀성、26례림파결음성유선암적혈청TRACP5b수평.결과 유선암조혈청TRACP5b수평위(3.85±0.85) U/L교건강조(2.08±0.84) U/L명현승고,차이유통계학의의(P＜0.05)；혈청TRACP5b예측림파결음성유선암골전이적민감성위42.31％,특이성위94.44％.결론 혈청TRACP5b재조기예측유선암골전이중적민감성화특이성량호,가작위진단유선암골전이적혈청표기물지일.
Objective To study the value of serum tartrate-resistant acid phosphatase 5b (TRACP5b) in bone metastasis in early breast cancer patients with negative axillary lymph nodes.Methods The serum level of TRACP5b was determined by enzyme-linked immumosorbent assay (ELISA) in 26 breast cancer patients and 18 healthy female adults.Results The serum level of TRACP5b was (3.85 ± 0.85) U/L in the group of breast cancer patients and (2.08 ± 0.84) U/L in the control group.The difference had statistical significance (P ＜0.05 ).The sensitivity was 42.31％ and the specificity was 94.44％ for TRACP5 b in predicting bone metastasis of breast cancer with negtive axillary lymph nodes.Conclusions TRACP5b has higher sensitivity and specificity in breast cancer patients than in healthy female adults.TRACP5b is a useful serum marker to predict bone metastasis in breast cancer patients.
