CAJ | 학술논문

目的分析不同类型垂体腺瘤的临床、病理、影像学特点,探讨垂体瘤诊断相关问题.方法回顾性研究746例垂体瘤患者的临床资料,包括临床表现、病理学、影像学特点.结果不同类型垂体瘤患者有其各自的临床特征,但以不同程度的压迫症状为主,或伴有激素水平异常的症状.催乳素>121.28μg/L时多考虑催乳素腺瘤(灵敏度79.9%,特异度97.2%).不同类型垂体腺瘤的体积有显著性差异(P<0.01),肿瘤侵袭性和肿瘤大小有显著正相关性(P<0.01).结论不同类型垂体瘤特点各异,需要针对不同类型的垂体瘤患者进行个体化诊断,治疗和预后评估.
목적 분석불동류형수체선류적림상、병리、영상학특점,탐토수체류진단상관문제.방법 회고성연구746례수체류환자적림상자료,포괄림상표현、병이학、영상학특점.결과 불동류형수체류환자유기각자적림상특정,단이불동정도적압박증상위주,혹반유격소수평이상적증상.최유소>121.28μg/L시다고필최유소선류(령민도79.9%,특이도97.2%).불동류형수체선류적체적유현저성차이(P<0.01),종류침습성화종류대소유현저정상관성(P<0.01).결론 불동류형수체류특점각이,수요침대불동류형적수체류환자진행개체화진단,치료화예후평고.
Objective To analyze the clinical data, including clinical features, treatment, and prognosis,in patients with different kinds of pituitary adenomas. Methods In this retrospective study, 746 cases were included. The characteristics of general epidemiology, clinical symptoms, pathology, imaging, treatment, and prognosis were analyzed. Results Clinical features were different among various pituitary adenomas. Symptoms caused by mass effect and hormone abnormality were expresssed in varying degrees. Serum prolactin>121.28 μg/L can differentiate the prolactin adenoma from the other huge tumor causing hyperprolactinemia due to the mass effect. There is significant relationship between the size and the various types of pituitary adenomas ( P<0.01 ),also between the size and the invasive capability ( P<0.01 ). Conclusions The pituitary adenomas may have their specific epidemiological, clinical, pathological, and imaging features, due to the distinct biological behavior. It is necessary to do the diagnosis, treatment, and prognosis evaluation individually.