CAJ | 학술논문

目的探讨生理性苍白球钙化患者陈述性记忆的改变,为苍白球损伤患者认知功能康复策略的制定提供理论依据.方法采用韦氏记忆量表中国版进行记忆测试和绘制遗忘曲线的方法对30例生理性苍白球钙化患者(实验组)和30例正常人(对照组)进行对照研究.结果实验组修订韦氏记忆量表中国版记忆商得分与对照组差异无显著性.2组之间遗忘曲线在时间间隔30 min时差异无显著性,在间隔2h后对照组的记忆保存率为(64.10±0.87)%,实验组为(44.83±1.57)%,差异有显著性.2h点的记忆保存率、9h点记忆保存率与苍白球钙化的体积大小呈负相关(r=-0.743和r=-0.483.P<0.01).1d以后,对照组的遗忘曲线的斜率为-1.95±0.48,实验组为-2.35±0.37,差异无显著性.结论生理性苍白球钙化患者在陈述性记忆的编码和提取上表现正常,在短期记忆转为长期记忆的记忆巩固过程中出现障碍.
목적 탐토생이성창백구개화환자진술성기억적개변,위창백구손상환자인지공능강복책략적제정제공이론의거.방법 채용위씨기억량표중국판진행기억측시화회제유망곡선적방법대30례생이성창백구개화환자(실험조)화30례정상인(대조조)진행대조연구.결과 실험조수정위씨기억량표중국판기억상득분여대조조차이무현저성.2조지간유망곡선재시간간격30 min시차이무현저성,재간격2h후대조조적기억보존솔위(64.10±0.87)%,실험조위(44.83±1.57)%,차이유현저성.2h점적기억보존솔、9h점기억보존솔여창백구개화적체적대소정부상관(r=-0.743화r=-0.483.P<0.01).1d이후,대조조적유망곡선적사솔위-1.95±0.48,실험조위-2.35±0.37,차이무현저성.결론 생이성창백구개화환자재진술성기억적편마화제취상표현정상,재단기기억전위장기기억적기억공고과정중출현장애.
Objective To study change of the declarative memory in patients with the calcification of the pallidum.Method The Chinese version of Wechsler Memory Scale(WMS-RC)test and dmwing forgetting curve were applied in 30 patients and 30 normal controls.Results There was no differences in the WMS-CR test's scores between the two groups.The patients had poorly memory preservation rate at the delays of 2 hours((64.10±0.87)%Vs(44.83±1.57)%,P<0.01),despite normal memory preservation rate over 30 mins and the similar slope after the delays of l day in the forgetting curve.There were negative correlations between the size of calcification and the memory preservation rate at the delays of 2 hours and 9 hours(r=-0.743,r=-0.483.P<0.01).Conclusion The results may reflect the effect of the pallidum on"slower confiolidation"declamtive memory process which aroused by a consequence of the repeated firing of hippocampal-neocortieal connections while the patients have normal memory encoding and retrieval.