国际中医中药杂志
國際中醫中藥雜誌
국제중의중약잡지
INTERNATIONAL JOURNAL OF TRIDITIONAL CHINESE MEDICINE
2011年
7期
612-616
,共5页
天然产物%药物发现%药物筛选
天然產物%藥物髮現%藥物篩選
천연산물%약물발현%약물사선
Natural products%Drug discovery%Drug screening
天然产物是药物发现与筛选的物质基础,高效、快速的药物筛选技术是获得天然产物线索化合物的重要前提.本文从药物研发环境、药物研发面临的困难、现代化的药物筛选技术、获得类似物的方法等方面综述了天然产物药物发现与药物筛选的现状及开发前景.
天然產物是藥物髮現與篩選的物質基礎,高效、快速的藥物篩選技術是穫得天然產物線索化閤物的重要前提.本文從藥物研髮環境、藥物研髮麵臨的睏難、現代化的藥物篩選技術、穫得類似物的方法等方麵綜述瞭天然產物藥物髮現與藥物篩選的現狀及開髮前景.
천연산물시약물발현여사선적물질기출,고효、쾌속적약물사선기술시획득천연산물선색화합물적중요전제.본문종약물연발배경、약물연발면림적곤난、현대화적약물사선기술、획득유사물적방법등방면종술료천연산물약물발현여약물사선적현상급개발전경.
Natural products were the material basis of drug discovery and drug screening, and high-performance techniques were the important prerequisite of earning hits. In this paper, we reviewed the current situation and future prospects of drug screening, including the pharmaceutical environment, the challenges facing drug discovery, the screening tools and the methods of generating analogs.