CAJ | 학술논문

目的：探讨具有双相作用的新型磁共振造影剂钆贝葡胺(Gd-BOPTA)对肝局灶性结节增生(FNH)的诊断价值。资料与方法对解放军总医院病理组织学证实或临床确诊的18例FNH患者共26个病灶进行回顾性分析，根据平扫及注射特异性对比剂钆贝葡胺后动态增强不同时期的形态、信号特征,包括病灶数目、大小、均匀度、强化形式、中央瘢痕、假包膜等进行比较分析,将病灶定义为典型与不典型,再对肝胆期典型与不典型病灶的信号特征进行评估。结果 MRI共发现26个病灶,19个病灶具有典型的形态及强化特征,在肝胆期,15个病灶为高信号,4个为等信号；均匀强化7个，环形强化8个。共7个病灶表现出不典型的形态或强化方式，在肝胆期这些病灶均存在摄取，5个呈高信号，2个呈等信号，由此诊断为FNH。结论钆贝葡胺在血液动力学期和肝胆期分别显示了FNH的形态学特征及其可摄取肝特异性对比剂的特性，对FNH的诊断有重要价值。
목적：탐토구유쌍상작용적신형자공진조영제구패포알(Gd-BOPTA)대간국조성결절증생(FNH)적진단개치。자료여방법대해방군총의원병리조직학증실혹림상학진적18례FNH환자공26개병조진행회고성분석，근거평소급주사특이성대비제구패포알후동태증강불동시기적형태、신호특정,포괄병조수목、대소、균균도、강화형식、중앙반흔、가포막등진행비교분석,장병조정의위전형여불전형,재대간담기전형여불전형병조적신호특정진행평고。결과 MRI공발현26개병조,19개병조구유전형적형태급강화특정,재간담기,15개병조위고신호,4개위등신호；균균강화7개，배형강화8개。공7개병조표현출불전형적형태혹강화방식，재간담기저사병조균존재섭취，5개정고신호，2개정등신호，유차진단위FNH。결론구패포알재혈액동역학기화간담기분별현시료FNH적형태학특정급기가섭취간특이성대비제적특성，대FNH적진단유중요개치。
Objective Analyze the diagnostic value of Gd-BOPTA enhanced MRI in the diagnosis of focal nodular hyperplasia (FNH) of the liver. Materials and Methods The MRI images of 26 lesions of FNH (18 cases) which were confirmed histopathologic or clinic examinations were reviewed retrospectively. The number, size, margin status, degree of homogeneity, enhancement pattern, presence of acenter scar, and presence of pseudocapsule of the lesions in various phases were analyzed. And the lesions were defined as typical and atypical on the basis of the elements which were describe as above. The characteristic performance of the lesions at hepatobiliary (excretory) phase were analyzed. Results A total of 26 lesions were depicted on MR images, and 19 lesions were defined as typical. A total of 15 lesions performed as hyperintense, 4 lesions performed as isotense, 8 lesions showed ring-like enhanced, 7 showed homogeneously enhanced in hepatobiliary (excretory) phase. The other 7 lesions presented atypical morphology and enhancement patterns, in which 5 lesions showed hyperintense and 4 lesions showed isointense in hepatobiliary (excretory) phase. Conclusion Gd-BOPTA enhanced MRI demonstrated the morphological characteristics of FNH and the uptake function of hepatic specific contrast agent, which is valuable in the diagnosis of FNH.