中国组织工程研究与临床康复
中國組織工程研究與臨床康複
중국조직공정연구여림상강복
JOURNAL OF CLINICAL REHABILITATIVE TISSUE ENGINEERING RESEARCH
2010年
9期
1595-1598
,共4页
吕雅平%李云鹤%刘轶凡%马洪顺
呂雅平%李雲鶴%劉軼凡%馬洪順
려아평%리운학%류질범%마홍순
老年人尸体%脊柱%青年人尸体%腰椎松质骨%剪切力%剪切应力%剪切应变%骨力学
老年人尸體%脊柱%青年人尸體%腰椎鬆質骨%剪切力%剪切應力%剪切應變%骨力學
노년인시체%척주%청년인시체%요추송질골%전절력%전절응력%전절응변%골역학
背景:骨质疏松、骨重建、骨再造、腰椎骨折固定器械的选择等都需要了解青年尸体和老年尸体腰椎松质骨的剪切力学特性.目的:比较老年尸体松质骨和青年尸体腰椎松质骨是否具有不同的剪切力学性质.方法:实验标本取自正常国人新鲜尸体4具,由白求恩医科大学解剖教研室提供,年龄分别为22,28,70,75岁.人死亡后1 h之内,解剖尸体取出腰段脊柱L_2~L_5标本.将标本沿前、后、左、右纵向切成长40 mm,宽5 mm,高5 mm的试样,在电子万能试验机上进行实验,以5 mm/min的实验速度对试样施加剪切力,实验结束后,打印机自动打印出剪切力、应变剪切应力等数据.观察每个试样的宏观断口形貌.结果与结论:剪切试样破坏后分别对两组试样的破坏断口进行大体观察发现,多数为横断口,少数为斜断口,青年组腰椎松质骨骨小粱排列细密,老年组腰椎松质骨骨小梁排列稀疏,孔隙较大.青年组剪切力、剪切应力和应变均显著高于老年组(37 19±3.25),(28.34±3.42)N;(1.49±0.13),(1.13±0.14)MPa;(1.40±0.50)%,(0.90±0.20)%,P<0.05].提示青年组脊柱腰椎松质骨和老年组脊柱腰椎松质骨具有不同的剪切力学特性.
揹景:骨質疏鬆、骨重建、骨再造、腰椎骨摺固定器械的選擇等都需要瞭解青年尸體和老年尸體腰椎鬆質骨的剪切力學特性.目的:比較老年尸體鬆質骨和青年尸體腰椎鬆質骨是否具有不同的剪切力學性質.方法:實驗標本取自正常國人新鮮尸體4具,由白求恩醫科大學解剖教研室提供,年齡分彆為22,28,70,75歲.人死亡後1 h之內,解剖尸體取齣腰段脊柱L_2~L_5標本.將標本沿前、後、左、右縱嚮切成長40 mm,寬5 mm,高5 mm的試樣,在電子萬能試驗機上進行實驗,以5 mm/min的實驗速度對試樣施加剪切力,實驗結束後,打印機自動打印齣剪切力、應變剪切應力等數據.觀察每箇試樣的宏觀斷口形貌.結果與結論:剪切試樣破壞後分彆對兩組試樣的破壞斷口進行大體觀察髮現,多數為橫斷口,少數為斜斷口,青年組腰椎鬆質骨骨小粱排列細密,老年組腰椎鬆質骨骨小樑排列稀疏,孔隙較大.青年組剪切力、剪切應力和應變均顯著高于老年組(37 19±3.25),(28.34±3.42)N;(1.49±0.13),(1.13±0.14)MPa;(1.40±0.50)%,(0.90±0.20)%,P<0.05].提示青年組脊柱腰椎鬆質骨和老年組脊柱腰椎鬆質骨具有不同的剪切力學特性.
배경:골질소송、골중건、골재조、요추골절고정기계적선택등도수요료해청년시체화노년시체요추송질골적전절역학특성.목적:비교노년시체송질골화청년시체요추송질골시부구유불동적전절역학성질.방법:실험표본취자정상국인신선시체4구,유백구은의과대학해부교연실제공,년령분별위22,28,70,75세.인사망후1 h지내,해부시체취출요단척주L_2~L_5표본.장표본연전、후、좌、우종향절성장40 mm,관5 mm,고5 mm적시양,재전자만능시험궤상진행실험,이5 mm/min적실험속도대시양시가전절력,실험결속후,타인궤자동타인출전절력、응변전절응력등수거.관찰매개시양적굉관단구형모.결과여결론:전절시양파배후분별대량조시양적파배단구진행대체관찰발현,다수위횡단구,소수위사단구,청년조요추송질골골소량배렬세밀,노년조요추송질골골소량배렬희소,공극교대.청년조전절력、전절응력화응변균현저고우노년조(37 19±3.25),(28.34±3.42)N;(1.49±0.13),(1.13±0.14)MPa;(1.40±0.50)%,(0.90±0.20)%,P<0.05].제시청년조척주요추송질골화노년조척주요추송질골구유불동적전절역학특성.
BACKGROUND:Shear mechanical properties of lumbar trabecular bone should be understood in treating osteoporosis,bone remodeling,bone reconstruction,as well as the choice of fracture fixed equipment.OBJECTIVE:To explore whether the shear mechanical properties of lumbar trabecular bone is different in young and aged normal fresh cadavers.METHODS:Experimental samples were from 4 normal fresh corpse,aged 22,28,70 and 75 years,were provided by Department of Anatomy,Norman Bethune Medical University.Spinal column thoracic vertebra L_2-L_5 specimen were obtained from corpse within 1 hour and cut into 40 min×5 mm×5 mm pieces.The specimen were tested on electronic universal testing machine with speed of 5 mm/min,the shear load,stress,strain and other data would be printed automatically,and the morphology of fracture surface was observed.RESULTS AND CONCLUSION:Majority of the fracture surfaces were comminuted,minority were transverse or oblique fracture.The macroscopic observation showed that trabecular arranged compact in the thoracic vertebra cancellous bone of the youth group,which was sparse arrangement and presented with senile osteoporosis in the aged group.The shear force,shear stress and strain of the youth group was greater than that of the aged group[(37.19±3.25),(28.34±3.42) N;(1.49+0.13),(1.13±0.14) MPa;(1.40±0.50)%,(0.90±0.20)%,P<0.05].It demonstrated that the impact mechanics properties of thoracic vertebra cancellous bone are different between the youth and aged groups.