CAJ | 학술논문

目的：对我院妥布霉素滴眼液进行制备和临床疗效观察，评价其生产的可行性与确切的临床疗效。方法：77例外眼细菌性感染患者，随机分成两组，以托百士滴眼液作为阳性药物进行对照试验，参照Gwon观察项目和计分的得分形式给予评价。结果：妥布霉素滴眼液和托百士滴眼液总有效率为92.7％和94.4％，相互对照，无显著性差异(P＜0.05)。结论：妥布霉素滴眼液制备工艺简单，疗效确切，可作为医院制剂推广。
목적：대아원타포매소적안액진행제비화림상료효관찰，평개기생산적가행성여학절적림상료효。방법：77예외안세균성감염환자，수궤분성량조，이탁백사적안액작위양성약물진행대조시험，삼조Gwon관찰항목화계분적득분형식급여평개。결과：타포매소적안액화탁백사적안액총유효솔위92.7％화94.4％，상호대조，무현저성차이(P＜0.05)。결론：타포매소적안액제비공예간단，료효학절，가작위의원제제추엄。
OBJECTIVE:To assess the feasibility of production and effects of Tobramycin eye drops prepared in this hospital for treating ocular infections .METHODS: 77 patients with external ocular infections were randomly divided into two groups with imported Tobrex as control drug to compare the effects.Assessment was made according to Gwon project results.RESULTS: Overall improvement rates were 92.7% in Tobramycin eye drops group and 94.4% in control group without significant difference between two groups(P＞ 0.05) .CONCLUSION: The technology of Tobramycin eye drops production is simple, therapeutic effect is satisfactory, and the production in hospital is feasible.