CAJ | 학술논문

目的评价珍黄胶囊治疗食管癌的抗癌增效作用和毒性。方法 1996年8月至1999年4月，64例病理确诊的食管癌病人随机分为二组：研究组(放疗+珍黄胶囊)；对照组(单纯放疗)，两组病人采用同样放疗方法和剂量。结果在放疗至40GY时，研究组和对照组的抗肿瘤有效率分别为46.9(15/32)和20%(6/30)(P<0.05)。放疗结束后一个月，研究组病人的完全缓解率37 .5%(12/32)，高于对照组20%(6/30)(P<0.05)。结论珍黄胶囊配合外照射可提高食管癌治疗的近期疗效。
목적평개진황효낭치료식관암적항암증효작용화독성。방법 1996년8월지1999년4월，64례병리학진적식관암병인수궤분위이조：연구조(방료+진황효낭)；대조조(단순방료)，량조병인채용동양방료방법화제량。결과재방료지40GY시，연구조화대조조적항종류유효솔분별위46.9(15/32)화20%(6/30)(P<0.05)。방료결속후일개월，연구조병인적완전완해솔37 .5%(12/32)，고우대조조20%(6/30)(P<0.05)。결론진황효낭배합외조사가제고식관암치료적근기료효。
Objective　To evaluate the anti-cancer effect an d toxicity of Zhen Huang in the treatment of esophageal carcinoma.Methods 　From August 1996 to April 1999,64 cases of pathologically proven esophag eal carcinoma were randomized into study group and control group,under the identical dosage and method of radiation.For the study g roup,patients were treated with radiotherapy combined Zhen Huang while patients in the control group received radiotherapy only.Results　At 40Gy of RT,the response rate was 46.9%(15/32)in the study group and 20%(6/30) in the control group (P<0.05).The complete response ra te at l month after radiation was 37.5%(12/32) in the study group and 20%(6/30)i n the control group (P<0.05).Conclusions　Radiation combined wit h Zhen Huang may im prove the immediate response rates in the treatment of esophageal carcinoma.