CAJ | 학술논문

目的：分析免疫功能正常患者原发性脑淋巴瘤影像诊断。方法：回顾性分析5例免疫功能正常，经病理证实的原发性脑淋巴瘤CT、MR和PET所见。结果：肿瘤可发生于幕上或幕下，可单发或多发。CT扫描多表现为等密度或稍高密度肿块，T1加权图像上呈低信号，T2加权图像呈等或高信号，CT和MR增强扫描病灶大多呈均匀明显强化。1例患者行PET检查，颅内肿瘤表现为高代谢改变。2例肿瘤分别于术后10、22个月复发。结论：原发性脑淋巴瘤少见，影像表现与其他颅内肿瘤所见互有重叠，鉴别比较困难，确诊主要依靠病理检查。
목적：분석면역공능정상환자원발성뇌림파류영상진단。방법：회고성분석5례면역공능정상，경병리증실적원발성뇌림파류CT、MR화PET소견。결과：종류가발생우막상혹막하，가단발혹다발。CT소묘다표현위등밀도혹초고밀도종괴，T1가권도상상정저신호，T2가권도상정등혹고신호，CT화MR증강소묘병조대다정균균명현강화。1례환자행PET검사，로내종류표현위고대사개변。2례종류분별우술후10、22개월복발。결론：원발성뇌림파류소견，영상표현여기타로내종류소견호유중첩，감별비교곤난，학진주요의고병리검사。
Objective:To describe the imaging findings of primary brain lymphoma in immunologically normal patients.Methods:The clinical manifestations and imaging findings of 5 patients operated with pathological proved primary brain lymphoma were reviewed.Results:In 5 cases,4 patients were men and one was woman.The median age was 47(range 34 to 63 years).Pathological diagnosis was compatible with primary non-Hodgkins lymphoma of brain for all five patients.Primary brain lymphoma may be soiltary or mutiple and locate at supratentorial or infratentorial.Lesions presented as an isodense to hyperdense on CT scan,hypointense on T1-weighted images and isointense or hyperintense to gray matter on T2-weighted images.Most lesions showed dense homogenous enhancement on CT and MR.Tumors associated with different degrees of mass effect.One patient received whole-body 18 FDG PET examination that presented as an intracranial hypermetabolic lesion.Conclusion:Primary brain lymphoma is a rare tumor that imaging findings overlap with those of other intracranial mass lesions,we can only make a suggestive diagnosis of primary brain lymphoma and pathological confirmation is meeded.