CAJ | 학술논문

目的：选用巯基代谢产物做为服用大蒜素的客观指标，来判定胃癌高发现场综合干预实验中受试对象服药的依从情况。方法：应用磷钨酸还原法测定受试对象尿液中巯基含量。结果：服用大蒜素组尿液巯基含量为10.41 U，明显高于未服用大蒜素组的2.94 U，P＜0.05。结论：对大规模人群干预实验中受试对象的生物样品中药物的代谢产物进行测定具有可行性，是一种重要的质量控制方法。
목적：선용구기대사산물주위복용대산소적객관지표，래판정위암고발현장종합간예실험중수시대상복약적의종정황。방법：응용린오산환원법측정수시대상뇨액중구기함량。결과：복용대산소조뇨액구기함량위10.41 U，명현고우미복용대산소조적2.94 U，P＜0.05。결론：대대규모인군간예실험중수시대상적생물양품중약물적대사산물진행측정구유가행성，시일충중요적질량공제방법。
Objective To evaluate the compliance situation in the intervention trial among the population atgastric cancer risk. Methods Detect the SH chemicals in the urine of people who have had garlic extracts. Re-sults The SH chemicals in the urine of the garlic extracts treatment group is 10.41 U/100 ml,the other groupis 2.94 U/100 ml. It is statistically significant that the mean value of SH chemicals was higher in the garlic ex-tracts treatment group. Conclusions Detecting the metabolites in the biosamples has its feasibihty in the largepopulation-based intervention trial,it is a good way for quality control.