肿瘤防治杂志
腫瘤防治雜誌
종류방치잡지
CHINA JOURNAL OF CANCER PREVENTION AND TREATMENT
2001年
1期
3-4
,共2页
关鹏%周宝森%张群弟%袁媛
關鵬%週寶森%張群弟%袁媛
관붕%주보삼%장군제%원원
胃肿瘤,流行病学%尿液%巯基测定
胃腫瘤,流行病學%尿液%巰基測定
위종류,류행병학%뇨액%구기측정
目的:选用巯基代谢产物做为服用大蒜素的客观指标,来判定胃癌高发现场综合干预实验中受试对象服药的依从情况。方法:应用磷钨酸还原法测定受试对象尿液中巯基含量。结果:服用大蒜素组尿液巯基含量为10.41 U,明显高于未服用大蒜素组的2.94 U,P<0.05。结论:对大规模人群干预实验中受试对象的生物样品中药物的代谢产物进行测定具有可行性,是一种重要的质量控制方法。
目的:選用巰基代謝產物做為服用大蒜素的客觀指標,來判定胃癌高髮現場綜閤榦預實驗中受試對象服藥的依從情況。方法:應用燐鎢痠還原法測定受試對象尿液中巰基含量。結果:服用大蒜素組尿液巰基含量為10.41 U,明顯高于未服用大蒜素組的2.94 U,P<0.05。結論:對大規模人群榦預實驗中受試對象的生物樣品中藥物的代謝產物進行測定具有可行性,是一種重要的質量控製方法。
목적:선용구기대사산물주위복용대산소적객관지표,래판정위암고발현장종합간예실험중수시대상복약적의종정황。방법:응용린오산환원법측정수시대상뇨액중구기함량。결과:복용대산소조뇨액구기함량위10.41 U,명현고우미복용대산소조적2.94 U,P<0.05。결론:대대규모인군간예실험중수시대상적생물양품중약물적대사산물진행측정구유가행성,시일충중요적질량공제방법。
Objective To evaluate the compliance situation in the intervention trial among the population atgastric cancer risk. Methods Detect the SH chemicals in the urine of people who have had garlic extracts. Re-sults The SH chemicals in the urine of the garlic extracts treatment group is 10.41 U/100 ml,the other groupis 2.94 U/100 ml. It is statistically significant that the mean value of SH chemicals was higher in the garlic ex-tracts treatment group. Conclusions Detecting the metabolites in the biosamples has its feasibihty in the largepopulation-based intervention trial,it is a good way for quality control.