CAJ | 학술논문

目的:本研究探讨生命早期食物短缺及营养不良对成年后糖尿病患病危险的影响,为国家制订糖尿病干预政策提供科学依据.方法:本研究运用重庆某医院体检中心资料,选取1959～1964年出生的4640例成人作为研究对象进行调查.其中将1959～1960年出生人群作为研究组,1962～1964年出生人群作为对照组,进行回顾性研究,比较两组人群平均血糖值和糖尿病的患病率以及分布状况.结果:本次调查的结果显示1960年出生人群的平均血糖(Blood slouse,BG)水平显著高于非饥荒年出生人群(P<0.05).饥荒年出生人群糖尿病患病率显著高于非饥荒年出生人群(P<0.05). 1960年出生人群糖尿病患病率最高为4.55%.1959、1960、1961年出生人群相对于非饥荒年出生人群的标化后相对危险度为3.33、3.48和3.45.结论:生命早期经历了食物短缺和营养不良等灾害可能会增加成年后患糖尿病的危险性.
목적:본연구탐토생명조기식물단결급영양불량대성년후당뇨병환병위험적영향,위국가제정당뇨병간예정책제공과학의거.방법:본연구운용중경모의원체검중심자료,선취1959～1964년출생적4640례성인작위연구대상진행조사.기중장1959～1960년출생인군작위연구조,1962～1964년출생인군작위대조조,진행회고성연구,비교량조인군평균혈당치화당뇨병적환병솔이급분포상황.결과:본차조사적결과현시1960년출생인군적평균혈당(Blood slouse,BG)수평현저고우비기황년출생인군(P<0.05).기황년출생인군당뇨병환병솔현저고우비기황년출생인군(P<0.05). 1960년출생인군당뇨병환병솔최고위4.55%.1959、1960、1961년출생인군상대우비기황년출생인군적표화후상대위험도위3.33、3.48화3.45.결론:생명조기경력료식물단결화영양불량등재해가능회증가성년후환당뇨병적위험성.
Objective:To examine the association between food shortage and malnutrition in earlier life and diabetes mellitus in adulthood,to provide evidence for formulation of the strategy for preventing diabetes mellitus. Methods:The data of medical examination center (MEC)of a certain hospital in Chongqing was gathered. People born during the period of 1959 to 1964 were enrolled in the research. The study group was born from 1959 to 1960. The control group was bom from 1962 to 1964. The attack rate and distribution of diabetes mellitus between two groups were compared by retrospective study. Results :The mean level of blood glucose was significantly higher in the 1960 group than that in non-famine group(P<0.05). The attack rate of diabetes mellitus was significantly higher in famine group than that in non-famine group(P<0.05). The highest mean of blood glucose was in 1960 group, accouting for 4.55%. Compared with the people who were born in 1962～1964, the standardization relative rates of 1959, 1960 and 1961 groups were 3.33,3.48 and 3.45, respectively.Conclusion: Higher risk of diabetes mellitus was caused by food shortage and malnutrition in fetal stage.