中华医学杂志
中華醫學雜誌
중화의학잡지
National Medical Journal of China
2010年
12期
839-843
,共5页
黄晓波%曾伟%欧阳凌云%刘雅%栾荣生%张廷杰%徐俊波%赵思勤%李秀钧%黄斌%魏东
黃曉波%曾偉%歐暘凌雲%劉雅%欒榮生%張廷傑%徐俊波%趙思勤%李秀鈞%黃斌%魏東
황효파%증위%구양릉운%류아%란영생%장정걸%서준파%조사근%리수균%황빈%위동
糖尿病前期%老年人%危险性评估
糖尿病前期%老年人%危險性評估
당뇨병전기%노년인%위험성평고
Prediabetic state%Aged%Risk assessment
目的 研究开发适合中老年人群的糖代谢异常患病危险度评估工具.方法 于2008年4至11月采用分层整群抽样的方法,在成都城乡地区40～79岁中老年人口中开展问卷调查,并进行血压、空腹血糖、葡萄糖75 g餐后血糖、血脂、血尿酸、身高、体质量、腰围等检测,共获取有效调查资料5205份.进行判别分析及多因素Logistic回归分析,建立量化评分体系,ROC分析筛选量化评分体系的界点,336例体检人群验证简易评分模型判别效能.结果 判别分析男女模型准确度分别为79.04%和81.35%.年龄、工作体力强度、体育锻炼、家族史、兄弟姐妹糖尿病史、体质指数、腹型肥胖和高血压病史8个指标构成男性简易评分模型;年龄、工作体力强度、体育锻炼、家族史、兄弟姐妹糖尿病史、体质指数、腹型肥胖、高血压病史、分娩次数和妊娠糖尿病史构成女性简易评分模型.ROC曲线下面积男性模型为0.702,女性模型为0.728.在其他人群应用中男性模型灵敏度和特异度分别为86.86%和65.12%,女性模型灵敏度和特异度分别为88.89%和72.97%.结论 初步开发的中老年人群糖代谢异常患病危险度评估工具简便可行,有一定实用性,可应用于中老年人群糖代谢异常的筛查.
目的 研究開髮適閤中老年人群的糖代謝異常患病危險度評估工具.方法 于2008年4至11月採用分層整群抽樣的方法,在成都城鄉地區40～79歲中老年人口中開展問捲調查,併進行血壓、空腹血糖、葡萄糖75 g餐後血糖、血脂、血尿痠、身高、體質量、腰圍等檢測,共穫取有效調查資料5205份.進行判彆分析及多因素Logistic迴歸分析,建立量化評分體繫,ROC分析篩選量化評分體繫的界點,336例體檢人群驗證簡易評分模型判彆效能.結果 判彆分析男女模型準確度分彆為79.04%和81.35%.年齡、工作體力彊度、體育鍛煉、傢族史、兄弟姐妹糖尿病史、體質指數、腹型肥胖和高血壓病史8箇指標構成男性簡易評分模型;年齡、工作體力彊度、體育鍛煉、傢族史、兄弟姐妹糖尿病史、體質指數、腹型肥胖、高血壓病史、分娩次數和妊娠糖尿病史構成女性簡易評分模型.ROC麯線下麵積男性模型為0.702,女性模型為0.728.在其他人群應用中男性模型靈敏度和特異度分彆為86.86%和65.12%,女性模型靈敏度和特異度分彆為88.89%和72.97%.結論 初步開髮的中老年人群糖代謝異常患病危險度評估工具簡便可行,有一定實用性,可應用于中老年人群糖代謝異常的篩查.
목적 연구개발괄합중노년인군적당대사이상환병위험도평고공구.방법 우2008년4지11월채용분층정군추양적방법,재성도성향지구40～79세중노년인구중개전문권조사,병진행혈압、공복혈당、포도당75 g찬후혈당、혈지、혈뇨산、신고、체질량、요위등검측,공획취유효조사자료5205빈.진행판별분석급다인소Logistic회귀분석,건립양화평분체계,ROC분석사선양화평분체계적계점,336례체검인군험증간역평분모형판별효능.결과 판별분석남녀모형준학도분별위79.04%화81.35%.년령、공작체력강도、체육단련、가족사、형제저매당뇨병사、체질지수、복형비반화고혈압병사8개지표구성남성간역평분모형;년령、공작체력강도、체육단련、가족사、형제저매당뇨병사、체질지수、복형비반、고혈압병사、분면차수화임신당뇨병사구성녀성간역평분모형.ROC곡선하면적남성모형위0.702,녀성모형위0.728.재기타인군응용중남성모형령민도화특이도분별위86.86%화65.12%,녀성모형령민도화특이도분별위88.89%화72.97%.결론 초보개발적중노년인군당대사이상환병위험도평고공구간편가행,유일정실용성,가응용우중노년인군당대사이상적사사.
Objective To develop the evaluation tool for the risk level of abnormal glucose metabolism morbidity in the middle-aged and elder populations. Methods By the stratified cluster sampling method, a survey was conducted in middle-aged and elder populations aged 40 -70 years old in urban and rural areas of Chengdu during April-November 2008. The parameters included blood pressure, fasting blood glucose, blood glucose after oral administration of 75 g glucose, blood lipid, blood uric acid, height, body weight and waistline, etc. A total of 5205 valid copies of questionnaires were obtained. A discriminant analysis and a multifactorial logistic regression analysis were conducted. The quantitative scoring system was established and the ROC analysis conducted to screen the boundary point of the quantitative scoring system. The discriminant performance of simple scoring model was conducted in 336 subjects for physical examination. Results The accuracies of discriminant analysis in male and female models were 79. 04% and 81.35% respectively. The simple male scoring mode included the following eight parameters: age, physical work intensity, parental history of diabetes mellitus, sibling's history of diabetes mellitus, BMI index, existing abdominal obesity and history of hypertension. The simple female scoring mode included the following eight parameters: age, physical work intensity, physical training, parental history of diabetes meUitus, sibling' s history of diabetes mellitus, BMI index, existing abdominal obesity, history of hypertension, number of parturition and history of gestational diabetes mellitus. The ROC AUCs were 0. 701 and 0. 728 in male and female models respectively. During applications in other populations, the sensitivity and specificity of the male model were 86. 86% and 65. 12% while those of female model 88. 89% and 72. 97% respectively. Conclusions The newly developed evaluation tool for the risk level of abnormal glucose metabolism morbidity in middle-aged and elder populations is both simple and practical. With an excellent practicability; it may be used to screen abnormal glucose metabolism in middle-aged and elder populations.
