中国组织工程研究与临床康复
中國組織工程研究與臨床康複
중국조직공정연구여림상강복
JOURNAL OF CLINICAL REHABILITATIVE TISSUE ENGINEERING RESEARCH
2008年
9期
1775-1781
,共7页
郭世炳%薛慧琴%冯卫%贾燕飞
郭世炳%薛慧琴%馮衛%賈燕飛
곽세병%설혜금%풍위%가연비
特制假体%置换%骨巨细胞瘤%骨肉瘤
特製假體%置換%骨巨細胞瘤%骨肉瘤
특제가체%치환%골거세포류%골육류
内蒙古医学院第二附属医院骨肿瘤科于1999-10/2006-08对33例骨肿瘤(恶性10例,良性23例)患者进行瘤段切除特制假体置换,假体材料为不锈钢或钴铬钼合金或钛合金,由北京力达康科技有限公司设计并定做.所有患者均同意外科手术并签订知情同意书和特制假体置换协议书.随访6~70个月,除1例髋骨体骨巨细胞瘤、2例滑膜肉瘤、1例恶性纤维组织细胞瘤患者死干肺转移外,其他病例无局部复发和转移,无骨折现象发生,1例膝关节术后感染并僵直,3例膝关节置换后大腿中段(假体与股骨连接处)疼痛:按Enneking肢体肌肉骨骼肿瘤外科治疗重建术后功能综合评分:上肢优良率80%;下肢优良率86.4%.肩关节疼痛缓解率为90%,主动活动增加;髋关节活动基本正常;膝关节屈伸活动0°~100°.1例膝关节不锈钢假体出现了排斥反应,2例考虑假体与股骨连接处松动,其他假体与组织的生物相容性较好.
內矇古醫學院第二附屬醫院骨腫瘤科于1999-10/2006-08對33例骨腫瘤(噁性10例,良性23例)患者進行瘤段切除特製假體置換,假體材料為不鏽鋼或鈷鉻鉬閤金或鈦閤金,由北京力達康科技有限公司設計併定做.所有患者均同意外科手術併籤訂知情同意書和特製假體置換協議書.隨訪6~70箇月,除1例髖骨體骨巨細胞瘤、2例滑膜肉瘤、1例噁性纖維組織細胞瘤患者死榦肺轉移外,其他病例無跼部複髮和轉移,無骨摺現象髮生,1例膝關節術後感染併僵直,3例膝關節置換後大腿中段(假體與股骨連接處)疼痛:按Enneking肢體肌肉骨骼腫瘤外科治療重建術後功能綜閤評分:上肢優良率80%;下肢優良率86.4%.肩關節疼痛緩解率為90%,主動活動增加;髖關節活動基本正常;膝關節屈伸活動0°~100°.1例膝關節不鏽鋼假體齣現瞭排斥反應,2例攷慮假體與股骨連接處鬆動,其他假體與組織的生物相容性較好.
내몽고의학원제이부속의원골종류과우1999-10/2006-08대33례골종류(악성10례,량성23례)환자진행류단절제특제가체치환,가체재료위불수강혹고락목합금혹태합금,유북경력체강과기유한공사설계병정주.소유환자균동의외과수술병첨정지정동의서화특제가체치환협의서.수방6~70개월,제1례관골체골거세포류、2례활막육류、1례악성섬유조직세포류환자사간폐전이외,기타병례무국부복발화전이,무골절현상발생,1례슬관절술후감염병강직,3례슬관절치환후대퇴중단(가체여고골련접처)동통:안Enneking지체기육골격종류외과치료중건술후공능종합평분:상지우량솔80%;하지우량솔86.4%.견관절동통완해솔위90%,주동활동증가;관관절활동기본정상;슬관절굴신활동0°~100°.1례슬관절불수강가체출현료배척반응,2례고필가체여고골련접처송동,기타가체여조직적생물상용성교호.
Thirty-three patients with bone tumor(malignant in 10 cases and benign in 23 cases)selected from Department of Bone Tumor,the Second Affiliated Hospital of Mongolian Medical College from October 1999 to August 2006 underwent special prostheric replacement at neoplastic segment.The prosthesis was made of stainless steel, alloy of cobalt-chrome-molybdenum,or titanium alloy,which are provided by Beijing Lidakang Technology Company Limited.All patients provided the conftrmed consent.In the follow-up of 6-70 menths,one patient with giant cell tumor of haunch bone,two patients with malignant synovioma,and one patient with malignant fibrous histiocytoma died due to pulITlonary metastasis.In all those patients who survived,none have local recidivation,transferring,or fracture.Among them,one patient had postoperative infection and rigor at knee joint.Three patients had ache at middle part of thigh(junction between prosthesis and femoral bone)after knee joint replacement.According to the Ennekhag scores after reconstruction of surgical oncology,fineness rate of upper limbs was 80%,and that of lower limbs was 86.4%.Odynolysis rate of shoulder ioint was 90%.Active movement was increased and activity of femoral articulation Was generally normal.Extension and flexion of knee joint ranged from 0 to 100 degree.Rejection occurred in stainless steel prosthesis of knee joint in one patient.Junction between prosthesis and femoral bone Was looge in two cases.All other prostheses had great biocompatibillty to tissues.