中医药信息
中醫藥信息
중의약신식
INFORMATION ON TRADITIONAL CHINESE MEDICINE
2011年
1期
35-38
,共4页
庞晓星%麻风华%王清华%张清波
龐曉星%痳風華%王清華%張清波
방효성%마풍화%왕청화%장청파
强力枇杷露%UPLC%吗啡%可待因%罂粟碱
彊力枇杷露%UPLC%嗎啡%可待因%罌粟堿
강력비파로%UPLC%마배%가대인%앵속감
目的:建立强力枇杷露中吗啡、可待因、罂粟碱三种成分的含量测定方法.方法:采用UPLC法同时测定吗啡、可待因、罂粟碱三种成分的含量并制定含量限度要求.色谱柱:ACQUHY UPLC HSS C18 (2.1mm×100mm,1.8μm);流动相:乙腈(A)-0.2%三氟乙酸(B),梯度洗脱;流速:0.4mL·min-1;检测波长:237nm.结果:吗啡、可待因、罂粟碱的线性范围依次为0.04008～3.206μg(r=0.9999),0.005980～0.4784μg(r=0.9999),0.0009984～0.07987μg(r=0.9999);平均回收率(n=6)依次为99.2%(RSD=1.0%),93.7%(RSD=2.6%),89.7%(RSD=2.2%).结论:本方法快速,简便,分离度好,提高了强力枇杷露的质量控制标准.
目的:建立彊力枇杷露中嗎啡、可待因、罌粟堿三種成分的含量測定方法.方法:採用UPLC法同時測定嗎啡、可待因、罌粟堿三種成分的含量併製定含量限度要求.色譜柱:ACQUHY UPLC HSS C18 (2.1mm×100mm,1.8μm);流動相:乙腈(A)-0.2%三氟乙痠(B),梯度洗脫;流速:0.4mL·min-1;檢測波長:237nm.結果:嗎啡、可待因、罌粟堿的線性範圍依次為0.04008～3.206μg(r=0.9999),0.005980～0.4784μg(r=0.9999),0.0009984～0.07987μg(r=0.9999);平均迴收率(n=6)依次為99.2%(RSD=1.0%),93.7%(RSD=2.6%),89.7%(RSD=2.2%).結論:本方法快速,簡便,分離度好,提高瞭彊力枇杷露的質量控製標準.
목적:건립강력비파로중마배、가대인、앵속감삼충성분적함량측정방법.방법:채용UPLC법동시측정마배、가대인、앵속감삼충성분적함량병제정함량한도요구.색보주:ACQUHY UPLC HSS C18 (2.1mm×100mm,1.8μm);류동상:을정(A)-0.2%삼불을산(B),제도세탈;류속:0.4mL·min-1;검측파장:237nm.결과:마배、가대인、앵속감적선성범위의차위0.04008～3.206μg(r=0.9999),0.005980～0.4784μg(r=0.9999),0.0009984～0.07987μg(r=0.9999);평균회수솔(n=6)의차위99.2%(RSD=1.0%),93.7%(RSD=2.6%),89.7%(RSD=2.2%).결론:본방법쾌속,간편,분리도호,제고료강력비파로적질량공제표준.
