中国基层医药
中國基層醫藥
중국기층의약
CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
2010年
6期
729-730
,共2页
胃肠道恶性间质瘤%诊断%治疗
胃腸道噁性間質瘤%診斷%治療
위장도악성간질류%진단%치료
GISS%Diagnosis%Treatment
目的 探讨胃肠道恶性间质瘤(GISS)的临床特点、病理学和免疫组化特点及诊断、治疗方法.方法 对36例GISS患者的临床资料和诊断、治疗进行回顾性分析.结果 GIST主要发生在胃和小肠,结肠和直肠较少;免疫组织化学检查显示CD117阳性33例(91. 7%),CD34阳性31例(86.1%);随访时间6～144个月,5年生存率31.8%.结论 GISS是一种少见的恶性肿瘤,其确诊有赖于病理组织学和免疫组化检查,CD34和CD117阳性在诊断上有其特殊意义;手术治疗仍是主要治疗手段.
目的 探討胃腸道噁性間質瘤(GISS)的臨床特點、病理學和免疫組化特點及診斷、治療方法.方法 對36例GISS患者的臨床資料和診斷、治療進行迴顧性分析.結果 GIST主要髮生在胃和小腸,結腸和直腸較少;免疫組織化學檢查顯示CD117暘性33例(91. 7%),CD34暘性31例(86.1%);隨訪時間6～144箇月,5年生存率31.8%.結論 GISS是一種少見的噁性腫瘤,其確診有賴于病理組織學和免疫組化檢查,CD34和CD117暘性在診斷上有其特殊意義;手術治療仍是主要治療手段.
목적 탐토위장도악성간질류(GISS)적림상특점、병이학화면역조화특점급진단、치료방법.방법 대36례GISS환자적림상자료화진단、치료진행회고성분석.결과 GIST주요발생재위화소장,결장화직장교소;면역조직화학검사현시CD117양성33례(91. 7%),CD34양성31례(86.1%);수방시간6～144개월,5년생존솔31.8%.결론 GISS시일충소견적악성종류,기학진유뢰우병리조직학화면역조화검사,CD34화CD117양성재진단상유기특수의의;수술치료잉시주요치료수단.
Objective To explore the clinical behavior,pathological and immunohistochemical characteristics and diagnosis, treatment methods of gastrointestinal stromal sarcomas (GISS). Methods Retrospective analysis was perfomed over 36 GISS patients based on clinical data and pathological data. Results GISS occurred more in the stomach and small intestine, than colon and rectum. Immunohistochemical staining showed CD117, CD34 expression,the positive rates were 91.7% and 86. 1%. Conclusion GISS is a rare malignant tumor, GISS diagnosis depends on the histologic and immunohistochemical test. CD34 and CD117 in the positive diagnosis has its special significance. Surgery is the main treatment.
