中国医药
中國醫藥
중국의약
CHINA MEDICINE
2011年
12期
1483-1484
,共2页
革兰阳性球菌%耐苯唑西林葡萄球菌%耐药性
革蘭暘性毬菌%耐苯唑西林葡萄毬菌%耐藥性
혁란양성구균%내분서서림포도구균%내약성
Gram-positive coccus%Meticillin-resistant Staphylococcus%Drug-resistance
目的 分析临床分离的革兰阳性球菌的感染情况和耐药特征,为临床用药提供依据.方法 收集山西省眼科医院2009年3月至2011年5月我院患者眼部标本分离培养、药物敏感试验.结果 共分离出革兰阳性球菌531株.其中金黄色葡萄球菌6株(1.13％),表皮葡萄球菌488株(91.90％),缓慢葡萄球菌18株(3.39％),科氏葡萄球菌科氏亚种3株(0.56％),哥伦比亚肠球菌9株(1.69％),链球菌属7株(1.32％).耐苯唑西林葡萄球菌(MRS)检出344株,检出率为70.51％.葡萄球菌属对多数抗菌药耐药严重,但未发现对万古霉素、利奈唑胺、喹努普汀/达福普汀、替考拉宁耐药耐药的菌株.对488株表皮葡萄球菌进行耐药情况检测,耐药株数分别为:氨苄西林/舒巴坦342株(70.08％)；苯唑西林342株(70.08％)；复方新诺明351株(71.93％)；红霉素390株(79.92％)；环丙沙星270株(55.33％)；克林霉素396株(81.15％)；利福平39株(7.99％)；莫西沙星15株(3.07％)；哌拉西林/他唑巴坦342株(70.08％)；青霉素G 487株(99.79％)；庆大霉素159株(32.58％)；四环素102株(20.90％).结论 耐苯唑西林葡萄球菌有很高发生率,大部分为凝固酶阴性的葡萄球菌,对大部分常用抗菌药耐药率很高.应加强院内感染控制,防止耐药菌株的产生.
目的 分析臨床分離的革蘭暘性毬菌的感染情況和耐藥特徵,為臨床用藥提供依據.方法 收集山西省眼科醫院2009年3月至2011年5月我院患者眼部標本分離培養、藥物敏感試驗.結果 共分離齣革蘭暘性毬菌531株.其中金黃色葡萄毬菌6株(1.13％),錶皮葡萄毬菌488株(91.90％),緩慢葡萄毬菌18株(3.39％),科氏葡萄毬菌科氏亞種3株(0.56％),哥倫比亞腸毬菌9株(1.69％),鏈毬菌屬7株(1.32％).耐苯唑西林葡萄毬菌(MRS)檢齣344株,檢齣率為70.51％.葡萄毬菌屬對多數抗菌藥耐藥嚴重,但未髮現對萬古黴素、利奈唑胺、喹努普汀/達福普汀、替攷拉寧耐藥耐藥的菌株.對488株錶皮葡萄毬菌進行耐藥情況檢測,耐藥株數分彆為:氨芐西林/舒巴坦342株(70.08％)；苯唑西林342株(70.08％)；複方新諾明351株(71.93％)；紅黴素390株(79.92％)；環丙沙星270株(55.33％)；剋林黴素396株(81.15％)；利福平39株(7.99％)；莫西沙星15株(3.07％)；哌拉西林/他唑巴坦342株(70.08％)；青黴素G 487株(99.79％)；慶大黴素159株(32.58％)；四環素102株(20.90％).結論 耐苯唑西林葡萄毬菌有很高髮生率,大部分為凝固酶陰性的葡萄毬菌,對大部分常用抗菌藥耐藥率很高.應加彊院內感染控製,防止耐藥菌株的產生.
목적 분석림상분리적혁란양성구균적감염정황화내약특정,위림상용약제공의거.방법 수집산서성안과의원2009년3월지2011년5월아원환자안부표본분리배양、약물민감시험.결과 공분리출혁란양성구균531주.기중금황색포도구균6주(1.13％),표피포도구균488주(91.90％),완만포도구균18주(3.39％),과씨포도구균과씨아충3주(0.56％),가륜비아장구균9주(1.69％),련구균속7주(1.32％).내분서서림포도구균(MRS)검출344주,검출솔위70.51％.포도구균속대다수항균약내약엄중,단미발현대만고매소、리내서알、규노보정/체복보정、체고랍저내약내약적균주.대488주표피포도구균진행내약정황검측,내약주수분별위:안변서림/서파탄342주(70.08％)；분서서림342주(70.08％)；복방신낙명351주(71.93％)；홍매소390주(79.92％)；배병사성270주(55.33％)；극림매소396주(81.15％)；리복평39주(7.99％)；막서사성15주(3.07％)；고랍서림/타서파탄342주(70.08％)；청매소G 487주(99.79％)；경대매소159주(32.58％)；사배소102주(20.90％).결론 내분서서림포도구균유흔고발생솔,대부분위응고매음성적포도구균,대대부분상용항균약내약솔흔고.응가강원내감염공제,방지내약균주적산생.
Objective To approach drug-resistance status of clinically isolated Gram-positive cocci in Shanxi Eye Hospital and to provide the evidence for clinically reasonable use of antibiotics.Methods A total of 531 strains of Gram-positive cocci were isolated from all kinds of eye specimens from Mar 2009 to May 2011 in Shanxi Eye Hospital.Organisms were cultivated and identified according to National Clinical Laboratory Operation Rule.The drug sensitivity testing was performed by MIC methods.Results Among the 531 strains,the isolating rate of Staphylococcus epidermidis ranked the first(488 strains).The detection rate of meticillin-resistant Staphyloccus epidermidis (MRSE)was 70.51％ (344 strains).The Gram-positive cocci were resistant to the commonly used antibiotics in different degrees except a 100％ sensitivity to Vancomycin,Teicoplanin,Linezolid,and Quinupristin/Dalfopristin.Conclusion We should strengthen the management of nosocomial infections to prevent the dissemination and epidemic of drug-resistant strains.
