中国临床实用医学
中國臨床實用醫學
중국림상실용의학
CHINA CLINICAL PRACTICAL MEDICINE
2008年
2期
17-18
,共2页
冠心病%高血压%血脂%血糖
冠心病%高血壓%血脂%血糖
관심병%고혈압%혈지%혈당
Coronary heart disease%Hypertension%Blood lipid%Blood sugar
目的 探讨冠心病的发病与高血压、血脂、血糖的关系.方法 抽取2000年1月至2006年1月住院、门诊及体检老年人(>60岁)共82例,以心电图,活动平板试验,心动超声,同位素扫描的检查结果分为冠心病组(46例)和非冠心病正常对照组(36例).合并其他心血管病的病例不在本项0研究的入选中.有服用降脂药物的患者,停服降脂药物2周后再检测血液的生化指标.两组均测定血脂、血糖、糖化血红蛋白(HbA1C)等生化指标,胰岛素用放免法测定,并计算胰岛素敏感指数ISI.结果 冠心病组患者同时合并有高血压的发生率显著高于对照组(P<0.05),冠心病组患者的低密度脂蛋白、血糖、HbA1C高于正常对照组(P<0.05).冠心病组患者的胰岛素敏感指数ISI低于正常对照组(P<0.05),两组三酰甘油、总胆同醇、高密度脂蛋白、载脂蛋白A、载脂蛋白B差异无统计学意义(P>0.05).结论 高血压作为冠心病的危险因素,是老年人防治冠心病的重点内容,降低LDL、血糖以及防治胰岛素抵抗对防治老年人的冠心病有积极的意义.
目的 探討冠心病的髮病與高血壓、血脂、血糖的關繫.方法 抽取2000年1月至2006年1月住院、門診及體檢老年人(>60歲)共82例,以心電圖,活動平闆試驗,心動超聲,同位素掃描的檢查結果分為冠心病組(46例)和非冠心病正常對照組(36例).閤併其他心血管病的病例不在本項0研究的入選中.有服用降脂藥物的患者,停服降脂藥物2週後再檢測血液的生化指標.兩組均測定血脂、血糖、糖化血紅蛋白(HbA1C)等生化指標,胰島素用放免法測定,併計算胰島素敏感指數ISI.結果 冠心病組患者同時閤併有高血壓的髮生率顯著高于對照組(P<0.05),冠心病組患者的低密度脂蛋白、血糖、HbA1C高于正常對照組(P<0.05).冠心病組患者的胰島素敏感指數ISI低于正常對照組(P<0.05),兩組三酰甘油、總膽同醇、高密度脂蛋白、載脂蛋白A、載脂蛋白B差異無統計學意義(P>0.05).結論 高血壓作為冠心病的危險因素,是老年人防治冠心病的重點內容,降低LDL、血糖以及防治胰島素牴抗對防治老年人的冠心病有積極的意義.
목적 탐토관심병적발병여고혈압、혈지、혈당적관계.방법 추취2000년1월지2006년1월주원、문진급체검노년인(>60세)공82례,이심전도,활동평판시험,심동초성,동위소소묘적검사결과분위관심병조(46례)화비관심병정상대조조(36례).합병기타심혈관병적병례불재본항0연구적입선중.유복용강지약물적환자,정복강지약물2주후재검측혈액적생화지표.량조균측정혈지、혈당、당화혈홍단백(HbA1C)등생화지표,이도소용방면법측정,병계산이도소민감지수ISI.결과 관심병조환자동시합병유고혈압적발생솔현저고우대조조(P<0.05),관심병조환자적저밀도지단백、혈당、HbA1C고우정상대조조(P<0.05).관심병조환자적이도소민감지수ISI저우정상대조조(P<0.05),량조삼선감유、총담동순、고밀도지단백、재지단백A、재지단백B차이무통계학의의(P>0.05).결론 고혈압작위관심병적위험인소,시노년인방치관심병적중점내용,강저LDL、혈당이급방치이도소저항대방치노년인적관심병유적겁적의의.
Objective To investigate the relationship between coronary heart disease in the aged and hypertension,blood lipid,blood sugar. Methods 82 cases of geriatric inpatients and outpatients(over 60 years old) from 2000 year to 2006 year were sampled and divided into two groups based on the results of electrocardio- gram, plate method,ultrasonic cardiogram, radioisotope scanning. Two groups were named group coronary heart disease(46 eases), and group normal control(36 cases). Patients taking any lipid-decreased medicine were r0e- quired to check the biochemical index of blood two weeks after stopping taking the medicine. The levels of blood lipid, blood sugar, HbA1 C were detected by biochemical methods. The levels of insulin were examined by Radio- immunoassay,and computed the insulin sensitivity index (ISI). Results Incidence of coronary heart disease combined with hypertension in coronary heart disease group was higher than that in control(P < 0. 05). The lev- els of low density lipoprotein(LDL) ,blood sugar, and HbA1C in the coronary heart disease group were signifi- cantly higher than those in controls. ISI the coronary heart disease group were significantly lower than that in controls. But there were no significant difference between the two groups in the levels of triglyeeride(TG)、total cholesterol(TC) 、high density lipoprotein(HDL)、Apo A,and Apo B. Conclusion Prevention and treatment of hypertension should be regarded as the key part against coronary heart disease in the aged. It is of positive signif- icance to lower level of LDL and sugar,and prevent the insulin resistance in protection from coronary heart dis- ease for the elders.
