CAJ | 학술논문

目的评价中文版肺功能状态和呼吸困难问卷(PFSDQ)修订版用于COPD患者的信度和效度.方法于2009年4-9月在北京市2家医院呼吸科门诊选取COPD稳定期患者61例,其中男52例,女9例;年龄51～80岁,平均(66±7)岁.用PFSDQ修订版和修订的英国医学委员会呼吸困难量表(MMRC量表)评估其呼吸困难及功能情况,并于同日或1周内进行检测肺功能和6 min步行试验.PFSDQ修订版包括活动受限程度、活动后呼吸困难和活动后疲乏3个维度.结果 PFSDQ修订版中活动受限、活动后呼吸困难和活动后疲乏3个维度的克龙巴赫α系数分别为0.84、0.85和0.89,与6 min步行距离、FEV_1、FEV_1/FVC、FEV_1占预计值%、MMRC测评的呼吸困难程度和BODE指数均有显著相关性(r值为-0.27～0.66,均P＜0.01).上述3个维度在病情严重程度不同的患者中进行两两比较,差异均有统计学意义(χ~2值为7.35～15.21,P＜0.05和P＜0.01).结论中文版PFSDQ修订版在61例COPD患者中使用具有良好的信度和效度,适用于我国COPD患者.
목적 평개중문판폐공능상태화호흡곤난문권(PFSDQ)수정판용우COPD환자적신도화효도.방법 우2009년4-9월재북경시2가의원호흡과문진선취COPD은정기환자61례,기중남52례,녀9례;년령51～80세,평균(66±7)세.용PFSDQ수정판화수정적영국의학위원회호흡곤난량표(MMRC량표)평고기호흡곤난급공능정황,병우동일혹1주내진행검측폐공능화6 min보행시험.PFSDQ수정판포괄활동수한정도、활동후호흡곤난화활동후피핍3개유도.결과 PFSDQ수정판중활동수한、활동후호흡곤난화활동후피핍3개유도적극룡파혁α계수분별위0.84、0.85화0.89,여6 min보행거리、FEV_1、FEV_1/FVC、FEV_1점예계치%、MMRC측평적호흡곤난정도화BODE지수균유현저상관성(r치위-0.27～0.66,균P＜0.01).상술3개유도재병정엄중정도불동적환자중진행량량비교,차이균유통계학의의(χ~2치위7.35～15.21,P＜0.05화P＜0.01).결론 중문판PFSDQ수정판재61례COPD환자중사용구유량호적신도화효도,괄용우아국COPD환자.
Objective To determine the reliability and validity of the modified pulmonary functional status and dyspnea questionnaire (PFSDQ-M) Chinese version in patients with chronic obstructive pulmonary disease (COPD) at 2 hospitals in Beijing,China.Methods PFSDQ-M has three domains,i.e.,change experienced by patient with activities or activity restriction (CA),dyspnea with activities (DA) and fatigue with activities (FA).Sixty-one patients with COPD in stable condition were assessed by interview with PFSDQ-M Chinese version,modified Medical Research Council dyspnea scale (MMRC),respectively,and underwent pulmonary function test (PFT) and 6-minute walking test (6MWT) on the same day or within one week before interview.Results Croabach's alpha was 0.84,0.85 and 0.89 for domains of CA,DA and FA of the PFSDQ-M,respectively.Scores of change in activities,dyspnea and fatigue with activities in patients of COPD correlated to their 6-minute walking distance (r =-0.39 to-0.50),FEV_1 (r =-0.28to-0.36),FEV_1/FVC (r =-0.27 to-0.37),FEV_1 % of predicted (r =-0.27 to-0.37),dyspnea score in MMRC (r = 0.59 to 0.66) and BODE index (r = 0.40 to 0.51),respectively (all P ＜ 0.01).Degrees of restriction of activity,dyspnea and fatigue with activities varied significantly in patients with different severity of COPD (χ~2 = 7.35 to 15.21,P ＜ 0.05,P ＜ 0.01,respectively).Conclusions Results of 61 patients with COPD interviewed with PFSDQ-M Chinese version suggest its good reliability and validity in discriminating patients with COPD of varied severity and stages.