CAJ | 학술논문

目的探讨多模式MRI在超急性期缺血性脑卒巾溶栓治疗中的应用价值.方法通过对发病12 h内的缺血性脑卒中患者116例行CT平扫及MR快速成像序列检查,共筛选界定为超急性期缺血性脑卒中41例(35.3%),并对其中33例患者行重组组织型纤溶酶原激活剂(rt-PA)静脉溶栓治疗及定期MR复查随访.结果 33例超急性期缺血性脑卒中患者行溶栓治疗后均预后良好,90 d改良Rankin评分均≤2分(平均1分),生活质量Barthal指数80～100分(平均95分);5例溶栓治疗后发牛无症状性脑出血(15.2%),其中1例为溶栓治疗后1周并发脑内血肿(PH1型),另4例溶栓治疗后6～24 h出现梗死局部少许渗血(HI型).结论在超急性期缺血性脑卒中溶栓治疗中,MRI对患者筛选界定和溶栓后复查均有较大应用价值,MRI指导的超急性期缺血性脑卒中静脉溶栓治疗是一种安全、有效的治疗方法.
목적 탐토다모식MRI재초급성기결혈성뇌졸건용전치료중적응용개치.방법 통과대발병12 h내적결혈성뇌졸중환자116례행CT평소급MR쾌속성상서렬검사,공사선계정위초급성기결혈성뇌졸중41례(35.3%),병대기중33례환자행중조조직형섬용매원격활제(rt-PA)정맥용전치료급정기MR복사수방.결과 33례초급성기결혈성뇌졸중환자행용전치료후균예후량호,90 d개량Rankin평분균≤2분(평균1분),생활질량Barthal지수80～100분(평균95분);5례용전치료후발우무증상성뇌출혈(15.2%),기중1례위용전치료후1주병발뇌내혈종(PH1형),령4례용전치료후6～24 h출현경사국부소허삼혈(HI형).결론재초급성기결혈성뇌졸중용전치료중,MRI대환자사선계정화용전후복사균유교대응용개치,MRI지도적초급성기결혈성뇌졸중정맥용전치료시일충안전、유효적치료방법.
Objective To investigate the value of MRI in thmmbolytic thempy of hyperacute cerebral arterial thrombosis.Methods One hundred and sixteen patients with acute cerebral arterial thrombosis were recruited.plain CT and multi.modal MRI were performed in all patients.Thirty-three patients with hyperacute cerebral infarction were treated bv recombinant tissue plasminogen activator(rt-PA) and followed-up periodically using MRI.Results The 33 patients with thrombolysis selected by MRI demonstrated clinical improvement.90 d moclified Rankin scale scores(mRs)were less than 2 and life quality Barthal indexes(BI)were from 80 to 100.The complication included one asymptomatic parenchymal hematoma(PH1)one weeks after thrombolytic therapy and 4(12.2%)hemorrhagic infarction(HI)6 to 24 hours after thrombolytic therapy.Condusions MRI has significant clinical value for the screening and follow-up of intravenous thrombolytic therapy of hyperacute ischemic stroke.MRI-based thrombolysis is a safe and effective method for hyperacute ischemic stroke.