CAJ | 학술논문

本文介绍了一种紫外一可见和荧光双通道铜离子探针,该探针基于罗丹明-B,通过水合肼为桥梁来连接三苯胺,便利而廉价.其在水体系下对铜离子显示出了良好的选择性和极高的灵敏度(2.78x10-8 mol·L-1).并且,通过初步的活细胞测试,表明该铜离子探针有着良好的生物相容性和细胞穿透性,在生物、医药领域有着非常大的潜力.
본문개소료일충자외일가견화형광쌍통도동리자탐침,해탐침기우라단명-B,통과수합정위교량래련접삼분알,편리이렴개.기재수체계하대동리자현시출료량호적선택성화겁고적령민도(2.78x10-8 mol·L-1).병차,통과초보적활세포측시,표명해동리자탐침유착량호적생물상용성화세포천투성,재생물、의약영역유착비상대적잠력.
An easy prepared fluorescence and UV-Vis dual channel probe for copper ion based on rhodamine-B, which exhibit high sensitivity (2.78x10-8 mol·L-1) and selectivity over other metal ions in mixed aqueous system (H2O:CH3CN=1:1 ,V/V), was developed and characterized. This probe involving rhodamine-B and triphenylamine together through the hydrazine bridge, could coordinate with Cu2+ and result in turn-on response in UV-Vis absorption and fluorescence. Furthermore, the cell stain experiments showed that compound 1 might be used for monitoring Cu2+ within biological samples.