国际医药卫生导报
國際醫藥衛生導報
국제의약위생도보
INTERNATIONAL MEDICINE & HEALTH GUIDANCE NEWS
2010年
20期
2468-2471
,共4页
金莉子%刘天民%马英东%陈筱潮
金莉子%劉天民%馬英東%陳篠潮
금리자%류천민%마영동%진소조
尿酸%冠心病%危险因素%SYNTAX评分
尿痠%冠心病%危險因素%SYNTAX評分
뇨산%관심병%위험인소%SYNTAX평분
Uric acid%Coronary artery disease%Risk factor%SYNTAX score
目的 探讨血清尿酸水平与不同方法评价的冠脉病变严重程度的关系.方法 对心血管内科住院并行冠状动脉造影检查的515例患者资料进行分析,按照冠脉造影结果分为冠心病组和冠脉造影结果正常组,冠心病组分别按照SYNTAX评分等级及冠脉病变血管支数评价病变程度,分别分析比较冠脉造影结果正常组与不同病变程度组的尿酸水平的差异.结果 血尿酸水平冠心病组(347.23±88.10)μmol/L,正常组(359.99±100.79)μmol/L,两组间的血尿酸水平比较差异无显著性(P＞0.05).SYNTAX评分和冠脉病变血管支数作为冠脉病变严重程度的标准而进行的分析,结果显示①以SYNTAX评分值作为标准分组,高危组(399.42±128.48)μmol/L均高于正常组的(347.23±88.10)μmol/L、低危组的(348.39±80.16)μ mol/L、中危组的(399.42±128.48)μ mol/L(P＜0.05);而造影结果正常组、低危组、中危组间的血尿酸比较差异无显著性(P＞0.05).②以冠脉病变血管支数作为标准分组,造影结果正常组(347.23±88.10)μmol/L、单支组(342.79±89.38)μmol/L、两支组(368.49±98.72)μmol/L、多支组(364.01±108.35)μmol/L,比较差异无显著性(P＞0.05).结论 冠心病合并高尿酸血症患者的冠脉SYNTAX评分高于正常尿酸水平冠心病患者,血尿酸独立地影响冠心病患者的冠脉病变严重程度,而单纯按照冠脉病变支数评价,未能发现血尿酸水平与冠脉病变程度之间相关性.
目的 探討血清尿痠水平與不同方法評價的冠脈病變嚴重程度的關繫.方法 對心血管內科住院併行冠狀動脈造影檢查的515例患者資料進行分析,按照冠脈造影結果分為冠心病組和冠脈造影結果正常組,冠心病組分彆按照SYNTAX評分等級及冠脈病變血管支數評價病變程度,分彆分析比較冠脈造影結果正常組與不同病變程度組的尿痠水平的差異.結果 血尿痠水平冠心病組(347.23±88.10)μmol/L,正常組(359.99±100.79)μmol/L,兩組間的血尿痠水平比較差異無顯著性(P＞0.05).SYNTAX評分和冠脈病變血管支數作為冠脈病變嚴重程度的標準而進行的分析,結果顯示①以SYNTAX評分值作為標準分組,高危組(399.42±128.48)μmol/L均高于正常組的(347.23±88.10)μmol/L、低危組的(348.39±80.16)μ mol/L、中危組的(399.42±128.48)μ mol/L(P＜0.05);而造影結果正常組、低危組、中危組間的血尿痠比較差異無顯著性(P＞0.05).②以冠脈病變血管支數作為標準分組,造影結果正常組(347.23±88.10)μmol/L、單支組(342.79±89.38)μmol/L、兩支組(368.49±98.72)μmol/L、多支組(364.01±108.35)μmol/L,比較差異無顯著性(P＞0.05).結論 冠心病閤併高尿痠血癥患者的冠脈SYNTAX評分高于正常尿痠水平冠心病患者,血尿痠獨立地影響冠心病患者的冠脈病變嚴重程度,而單純按照冠脈病變支數評價,未能髮現血尿痠水平與冠脈病變程度之間相關性.
목적 탐토혈청뇨산수평여불동방법평개적관맥병변엄중정도적관계.방법 대심혈관내과주원병행관상동맥조영검사적515례환자자료진행분석,안조관맥조영결과분위관심병조화관맥조영결과정상조,관심병조분별안조SYNTAX평분등급급관맥병변혈관지수평개병변정도,분별분석비교관맥조영결과정상조여불동병변정도조적뇨산수평적차이.결과 혈뇨산수평관심병조(347.23±88.10)μmol/L,정상조(359.99±100.79)μmol/L,량조간적혈뇨산수평비교차이무현저성(P＞0.05).SYNTAX평분화관맥병변혈관지수작위관맥병변엄중정도적표준이진행적분석,결과현시①이SYNTAX평분치작위표준분조,고위조(399.42±128.48)μmol/L균고우정상조적(347.23±88.10)μmol/L、저위조적(348.39±80.16)μ mol/L、중위조적(399.42±128.48)μ mol/L(P＜0.05);이조영결과정상조、저위조、중위조간적혈뇨산비교차이무현저성(P＞0.05).②이관맥병변혈관지수작위표준분조,조영결과정상조(347.23±88.10)μmol/L、단지조(342.79±89.38)μmol/L、량지조(368.49±98.72)μmol/L、다지조(364.01±108.35)μmol/L,비교차이무현저성(P＞0.05).결론 관심병합병고뇨산혈증환자적관맥SYNTAX평분고우정상뇨산수평관심병환자,혈뇨산독입지영향관심병환자적관맥병변엄중정도,이단순안조관맥병변지수평개,미능발현혈뇨산수평여관맥병변정도지간상관성.
Objective To explore the association of serum UA level with the severity of coronary artery disease (CAD) assessed by different methods. Methods Five-hundred and fifteen patients with suspected CAD received coronary angiography and were divided into normal group and CAD group; the severity of CAD was assessed based on the SYNTAX score and the number of stenosis. Serum UA levels were compared between the normal and CAD group with different severity. Results The average UA level in high-risk group for SYNTAX score was significantly higher than that of in the normal, low-risk, or moderate-risk group; UA level did not differ significantly among the normal group and univessel disease, twovessel disease, and multi-vessel disease groups. Conclusions CAD patients with hyperuricemia have higher SYNTAX wores than those with normal serum UA level. Uric ac id is independently assoc iated with the severity of CAD. But this association can not he found as the severity of CAD was determined by the number of stenotic vessels.
