CAJ | 학술논문

目的探讨福爱乐医用胶(主要成分为α-氰基丙烯酸正辛酯和α-氰基丙烯酸正丁酯)在颅内动静脉畸形(CAVM)血管内治疗中的临床疗效.方法局麻下经股动脉穿刺插管,微导管超选择插管至颅内病变部位,用福爱乐医用胶栓塞治疗CAVM 15例.其中病灶直径大于6 cm者4例,3.～6 cm者7例,小于3 cm者4例.单支供血者3例,2支供血者5例,3支供血者7例.栓塞加手术切除3例,栓塞后行伽马刀治疗2例.结果 15例患者共行26次栓塞治疗,8例J获80％以上栓塞,其中5例完全栓塞；5例获50％～80％栓塞；2例栓塞小于50％.所有患者手术过程中均未发生严重粘管情况.结论福爱乐医胶治疗CAVM安全有效,是较为理想的栓塞材料.
목적 탐토복애악의용효(주요성분위α-청기병희산정신지화α-청기병희산정정지)재로내동정맥기형(CAVM)혈관내치료중적림상료효.방법 국마하경고동맥천자삽관,미도관초선택삽관지로내병변부위,용복애악의용효전새치료CAVM 15례.기중병조직경대우6 cm자4례,3.～6 cm자7례,소우3 cm자4례.단지공혈자3례,2지공혈자5례,3지공혈자7례.전새가수술절제3례,전새후행가마도치료2례.결과 15례환자공행26차전새치료,8례J획80％이상전새,기중5례완전전새；5례획50％～80％전새；2례전새소우50％.소유환자수술과정중균미발생엄중점관정황.결론 복애악의효치료CAVM안전유효,시교위이상적전새재료.
[Objective]To study the clinical efficacy of embolization in treating cerebral arteriovenous malformations(AVMs) using a new liquid embolic agent,FuAiLe medical adhesive (FAL,main ingredients:α-octyl cyanoacrylate and α-butyl cyanoacrylate).[Methods]Femoral artery was catheterized under local anesthesia,and then superselective catheterization to intracranial lesions were obtained using marathon 1.3F microcatheter.Fifteen cerebral AVMs were embolized by FAL.The diameter of AVMs was larger than 6 cm in 4 cases,3-6 cm in 7 cases and smaller than 3 cm in 4 cases.Single blood supply was observed in 3 cases,2 blood supplies in 5 cases and 3 blood supplies in 7 cases.Surgical ablation was applied after embolization in 3 cases,and gamma knife treatment was applied after embolization in 2 cases,[Results] A total of 26-time embolization was obtained in 15 patients;more than 80％ embolization was achieved in 8 cases,including 5 with complete embolization;and 50％-80％ embolization was achieved in 5 cases;less than 50％ embolization was achieved in only 2 cases.No serious complication associated with embolization was noted in all patients.[Conclusion] It is safe and effective for FAL to treat cerebral AVMs and FAL may be an ideal embolic agent.