中国综合临床
中國綜閤臨床
중국종합림상
CLINICAL MEDICINE OF CHINA
2010年
9期
931-932
,共2页
连续性血液净化%重症急性胰腺炎
連續性血液淨化%重癥急性胰腺炎
련속성혈액정화%중증급성이선염
Continuous blood purification%Severe acute pancreatitis
目的 观察连续性血液净化(CBP)治疗在重症急性胰腺炎(SAP)患者治疗中的作用.方法 将26例SAP患者随机分为常规组和CBP组,常规组给予传统常规治疗,CBP组在常规治疗基础上,给予CBP治疗.观察2组患者治疗前及治疗后2、5 d的APACHEⅡ评分、C-反应蛋白(CRP);2组的机械通气时间、住ICU时间及病死率.结果 常规组治疗2、5 d后的APACHEⅡ评分为:11.61±3.00、10.76±4.30,CRP为:(149.71±60.06)、(101.21±33.98)mg/L;CBP组相应为:8.20±1.87、6.19±1.49,(109.17±23.91)、(70.83±25.45)mg/L,2组间差异有统计学意义(P均＜0.05);常规组机械通气时间、住ICU时间、病死率为:(13.29±6.23)、(16.00±6.86)d,21.43%(3/14);CBP组相应为(8.00±5.27)、(10.33±4.81)d,8.33%(1/12),2组间差异有统计学意义(P均＜0.05).结论 CBP可以有效改善SAP患者的APACHEⅡ评分,降低CRP,缩短机械通气时间及住ICU时间,降低病死率,应在临床工作中推广应用.
目的 觀察連續性血液淨化(CBP)治療在重癥急性胰腺炎(SAP)患者治療中的作用.方法 將26例SAP患者隨機分為常規組和CBP組,常規組給予傳統常規治療,CBP組在常規治療基礎上,給予CBP治療.觀察2組患者治療前及治療後2、5 d的APACHEⅡ評分、C-反應蛋白(CRP);2組的機械通氣時間、住ICU時間及病死率.結果 常規組治療2、5 d後的APACHEⅡ評分為:11.61±3.00、10.76±4.30,CRP為:(149.71±60.06)、(101.21±33.98)mg/L;CBP組相應為:8.20±1.87、6.19±1.49,(109.17±23.91)、(70.83±25.45)mg/L,2組間差異有統計學意義(P均＜0.05);常規組機械通氣時間、住ICU時間、病死率為:(13.29±6.23)、(16.00±6.86)d,21.43%(3/14);CBP組相應為(8.00±5.27)、(10.33±4.81)d,8.33%(1/12),2組間差異有統計學意義(P均＜0.05).結論 CBP可以有效改善SAP患者的APACHEⅡ評分,降低CRP,縮短機械通氣時間及住ICU時間,降低病死率,應在臨床工作中推廣應用.
목적 관찰련속성혈액정화(CBP)치료재중증급성이선염(SAP)환자치료중적작용.방법 장26례SAP환자수궤분위상규조화CBP조,상규조급여전통상규치료,CBP조재상규치료기출상,급여CBP치료.관찰2조환자치료전급치료후2、5 d적APACHEⅡ평분、C-반응단백(CRP);2조적궤계통기시간、주ICU시간급병사솔.결과 상규조치료2、5 d후적APACHEⅡ평분위:11.61±3.00、10.76±4.30,CRP위:(149.71±60.06)、(101.21±33.98)mg/L;CBP조상응위:8.20±1.87、6.19±1.49,(109.17±23.91)、(70.83±25.45)mg/L,2조간차이유통계학의의(P균＜0.05);상규조궤계통기시간、주ICU시간、병사솔위:(13.29±6.23)、(16.00±6.86)d,21.43%(3/14);CBP조상응위(8.00±5.27)、(10.33±4.81)d,8.33%(1/12),2조간차이유통계학의의(P균＜0.05).결론 CBP가이유효개선SAP환자적APACHEⅡ평분,강저CRP,축단궤계통기시간급주ICU시간,강저병사솔,응재림상공작중추엄응용.
Objective To investigate the effect of continuous blood purification(CBP) in the patients with severe acute pancreatitis(SAP). Methods Twenty-six patients with severe acute pancreatitis were divided into the control group and the observation group randomly. Fourteen cases in the control group were given conventional treatment only, 12 cases in CBP group were given continuous blood purification as well as the conventional treatment. The APACHE Ⅱ score and CRP of pre- and intra-treatment at the 2nd and 5th day were observed in the two groups. The duration of mechanical ventilation, the duration of ICU stay, the mortality of hospital were observed as well. Results The APACHE Ⅱ score and CRP of the second day and the fifth day of intra-treatment in the control group were 1.61±3.00,10.76±4.30, (149.71±60.06) mg/L and (101.21±33.98) mg/L, respectively, which were significantly different to those of (8.20±1.87) mg/L, (6.19±1.49) mg/L, (109.17±23.91) mg/L,(70.83±25.45)mg/L in the CBP group(P＜0.05). The duration of mechanical ventilation,the duration of ICU stay and the mortality of hospital were (13.29 ± 6.23) d, (16.00 ± 6.86) d, 21.43% in the control group, which were significantly lower than those of (8.00 ±5.27)d,(10.33 ±4.81)d,8.33% in the other group (P ＜0.05).Conclusions CBP is an effective method for the patients with severe acute pancreatitis to shorten the duration of mechanical ventilation and the ICU stay,and decrease the mortality of hospital.
