神经损伤与功能重建
神經損傷與功能重建
신경손상여공능중건
NEURAL INJURY AND FUNCTIONAL RECONSTRUCTION
2013年
4期
263-265
,共3页
脑后部可逆性脑病综合征%临床表现%影像学特征
腦後部可逆性腦病綜閤徵%臨床錶現%影像學特徵
뇌후부가역성뇌병종합정%림상표현%영상학특정
posterior reversible encephalopathy syndrome%clinical manifestations%imaging features
目的：探讨脑后部可逆性脑病综合征(PRES)的临床表现及影像学特征。方法：对我院确诊的3例及国内文献报道的129例PRES患者的临床资料进行回顾性分析。结果：132例PRES患者中，男27例，女105例；基础病以妊娠相关72例(54.55%)，原发性高血压(15.91%)为主；血压增高(92.42%)，头痛、头晕(93.18%)，意识障碍(59.85%)，视觉障碍(59.85%)，癫痫发作(56.82%)为最常见表现；脑MRI主要表现T1WI病灶等或略低信号，T2WI、FLAIR呈高信号，DWI等或稍低信号，ADC呈高信号，病变主要位于顶枕叶(81.75%)；临床及影像学表现1~2周后好转。结论：PRES是主要以血压增高，具有特征性的可逆性临床和影像表现的一组神经系统综合征，若及时治疗，预后良好。
目的：探討腦後部可逆性腦病綜閤徵(PRES)的臨床錶現及影像學特徵。方法：對我院確診的3例及國內文獻報道的129例PRES患者的臨床資料進行迴顧性分析。結果：132例PRES患者中，男27例，女105例；基礎病以妊娠相關72例(54.55%)，原髮性高血壓(15.91%)為主；血壓增高(92.42%)，頭痛、頭暈(93.18%)，意識障礙(59.85%)，視覺障礙(59.85%)，癲癇髮作(56.82%)為最常見錶現；腦MRI主要錶現T1WI病竈等或略低信號，T2WI、FLAIR呈高信號，DWI等或稍低信號，ADC呈高信號，病變主要位于頂枕葉(81.75%)；臨床及影像學錶現1~2週後好轉。結論：PRES是主要以血壓增高，具有特徵性的可逆性臨床和影像錶現的一組神經繫統綜閤徵，若及時治療，預後良好。
목적：탐토뇌후부가역성뇌병종합정(PRES)적림상표현급영상학특정。방법：대아원학진적3례급국내문헌보도적129례PRES환자적림상자료진행회고성분석。결과：132례PRES환자중，남27례，녀105례；기출병이임신상관72례(54.55%)，원발성고혈압(15.91%)위주；혈압증고(92.42%)，두통、두훈(93.18%)，의식장애(59.85%)，시각장애(59.85%)，전간발작(56.82%)위최상견표현；뇌MRI주요표현T1WI병조등혹략저신호，T2WI、FLAIR정고신호，DWI등혹초저신호，ADC정고신호，병변주요위우정침협(81.75%)；림상급영상학표현1~2주후호전。결론：PRES시주요이혈압증고，구유특정성적가역성림상화영상표현적일조신경계통종합정，약급시치료，예후량호。
Objective:To explore the clinical manifestations and imaging features of posterior reversible encephalopathy syndrome (PRES). Methods:The clinical data of 3 patients diagnosed with PRES in our hospital and another 129 patients from literatures were analyzed retrospectively. Results:In 132 cases, 27 were males and 105 were females. The etiology was mainly related to pregnancy (54.55%) and primary hypertension (15.91%). Hypertension (92.42%), headache (93.18%), consciousness disorder (59.85%),vi-sual disturbances (59.85%) and epileptic attacks (56.82%) were described as the most common presenting symptoms. MRI showed iso-intensity or mild hypo-intensity on T1WI, hyper-intensity on T2WI and FLAIR, iso-intensity or mild hypo-intensity on DWI, and hyper-intensity on ADC. The lesions were main-ly located in the parietal and occipital lobes (81.75%). The clinical and imaging manifestations could im-prove in 1~2 weeks. Conclusion:PRES is a neurological syndrome with an elevation of blood pressure, having distinctive reversible clinical and imaging manifestations. The prognosis will be good if the treat-ment is timely given.
