华西药学杂志
華西藥學雜誌
화서약학잡지
WEST CHINA JOURNAL OF PHARMACEUTICAL SCIENCES
2006年
5期
416-419
,共4页
江洪波%田祥琴%胡小兵%黄静%孙奇%陈渝
江洪波%田祥琴%鬍小兵%黃靜%孫奇%陳渝
강홍파%전상금%호소병%황정%손기%진투
麦冬%二氢高异黄酮%圆二色谱%立体构型
麥鼕%二氫高異黃酮%圓二色譜%立體構型
맥동%이경고이황동%원이색보%입체구형
目的 研究麦冬中几种二氢高异黄酮的立体结构.方法 采用光谱方法 ,并用圆二色谱确定立体结构.结果 确定6个二氢高异黄酮的立体结构,鉴定结果 为:5,7-dihydroxy-6-methyl-8-methoxy-3(R)-(2'-hydroxy-4'-methoxybenzyl)chroman-4 -one(Ⅰa);5,7-dihydroxy-6-methyl-8-methoxy-3(S)-(2'-hydroxy-4'-methoxybenzyl)chroman-4-one(Ⅰb);5,7-dihydroxy-6,8-dimethyl-3(R)-(3'-methoxy-4'-hydroxybenzyl) chroman-4-one(Ⅱa) ;5,7-dihydroxy-6,8-dimethyl-3(S)-(3'-methoxy-4' -hydroxybenzyl)chroman-4-one(Ⅱb);R-methylophiopogonanone B (Ⅲ)和R-methylophiopogonanone A (Ⅳ).结论 首次确定了6个二氢高异黄酮(Ⅰ～Ⅳ)的立体构型.
目的 研究麥鼕中幾種二氫高異黃酮的立體結構.方法 採用光譜方法 ,併用圓二色譜確定立體結構.結果 確定6箇二氫高異黃酮的立體結構,鑒定結果 為:5,7-dihydroxy-6-methyl-8-methoxy-3(R)-(2'-hydroxy-4'-methoxybenzyl)chroman-4 -one(Ⅰa);5,7-dihydroxy-6-methyl-8-methoxy-3(S)-(2'-hydroxy-4'-methoxybenzyl)chroman-4-one(Ⅰb);5,7-dihydroxy-6,8-dimethyl-3(R)-(3'-methoxy-4'-hydroxybenzyl) chroman-4-one(Ⅱa) ;5,7-dihydroxy-6,8-dimethyl-3(S)-(3'-methoxy-4' -hydroxybenzyl)chroman-4-one(Ⅱb);R-methylophiopogonanone B (Ⅲ)和R-methylophiopogonanone A (Ⅳ).結論 首次確定瞭6箇二氫高異黃酮(Ⅰ～Ⅳ)的立體構型.
목적 연구맥동중궤충이경고이황동적입체결구.방법 채용광보방법 ,병용원이색보학정입체결구.결과 학정6개이경고이황동적입체결구,감정결과 위:5,7-dihydroxy-6-methyl-8-methoxy-3(R)-(2'-hydroxy-4'-methoxybenzyl)chroman-4 -one(Ⅰa);5,7-dihydroxy-6-methyl-8-methoxy-3(S)-(2'-hydroxy-4'-methoxybenzyl)chroman-4-one(Ⅰb);5,7-dihydroxy-6,8-dimethyl-3(R)-(3'-methoxy-4'-hydroxybenzyl) chroman-4-one(Ⅱa) ;5,7-dihydroxy-6,8-dimethyl-3(S)-(3'-methoxy-4' -hydroxybenzyl)chroman-4-one(Ⅱb);R-methylophiopogonanone B (Ⅲ)화R-methylophiopogonanone A (Ⅳ).결론 수차학정료6개이경고이황동(Ⅰ～Ⅳ)적입체구형.
