临床麻醉学杂志
臨床痳醉學雜誌
림상마취학잡지
THE JOURNAL OF CLINICAL ANESTHESIOLOGY
2010年
2期
113-114
,共2页
杭黎华%邵东华%王洪%周蓓%黄霞萍%顾月萍
杭黎華%邵東華%王洪%週蓓%黃霞萍%顧月萍
항려화%소동화%왕홍%주배%황하평%고월평
氯胺酮%雷米芬太尼%痛觉过敏
氯胺酮%雷米芬太尼%痛覺過敏
록알동%뢰미분태니%통각과민
Ketamine%Remifentanil%Hyperalgesia
目的 测定氯胺酮减轻雷米芬太尼致术后痛觉过敏的半数有效量(ED_(50)).方法 选择48例ASA Ⅰ或Ⅱ级择期全麻腹腔镜下行胆囊切除术的成年患者,用点斜法测定氯胺酮减轻雷米芬太尼致术后痛觉过敏的ED_(50).结果 氯胺酮减轻雷米芬太尼致术后痛觉过敏的ED_(50)为0.23 mg/kg(95%可信区间:0.08～0.39 mg/kg).ED_(50)为0.68 mg/kg(95%可信区间:0.41～1.92mg/kg).结论 氯胺酮减轻雷米芬太尼致术后痛觉过敏的ED_(50)为0.23 mg/kg.
目的 測定氯胺酮減輕雷米芬太尼緻術後痛覺過敏的半數有效量(ED_(50)).方法 選擇48例ASA Ⅰ或Ⅱ級擇期全痳腹腔鏡下行膽囊切除術的成年患者,用點斜法測定氯胺酮減輕雷米芬太尼緻術後痛覺過敏的ED_(50).結果 氯胺酮減輕雷米芬太尼緻術後痛覺過敏的ED_(50)為0.23 mg/kg(95%可信區間:0.08～0.39 mg/kg).ED_(50)為0.68 mg/kg(95%可信區間:0.41～1.92mg/kg).結論 氯胺酮減輕雷米芬太尼緻術後痛覺過敏的ED_(50)為0.23 mg/kg.
목적 측정록알동감경뢰미분태니치술후통각과민적반수유효량(ED_(50)).방법 선택48례ASA Ⅰ혹Ⅱ급택기전마복강경하행담낭절제술적성년환자,용점사법측정록알동감경뢰미분태니치술후통각과민적ED_(50).결과 록알동감경뢰미분태니치술후통각과민적ED_(50)위0.23 mg/kg(95%가신구간:0.08～0.39 mg/kg).ED_(50)위0.68 mg/kg(95%가신구간:0.41～1.92mg/kg).결론 록알동감경뢰미분태니치술후통각과민적ED_(50)위0.23 mg/kg.
Objective To determine the ED_(50) of ketarnine for alleviating postoperative hyperaigesia after remifentanil-hased anesthesia in patients. Methods Forty-eight ASA Ⅰ or Ⅱpatients undergoing laparoscopic choleeystectomy during remifentanil-hased general anesthesia. The ED_(50) of ketamine for alleviating postoperative hyperalgesia was determined by spot-slope method. Results The ED_(50) of ketamine for that was 0. 23 mg/kg (95%CI,0. 08-0. 39 mg/kg) and ED_(95) was 0. 68 mg/kg (95% CI, 0. 41-1.92 mg/kg). Conclusion The ED_(50) of ketamine was 0. 23 mg/kg for alleviating postoperative hyperaigesia after remifentanil-hased anesthesia.
