中华眼外伤职业眼病杂志
中華眼外傷職業眼病雜誌
중화안외상직업안병잡지
CHINESE JOURNAL OF OCULAR TRAUMA AND OCCUPATIONAL EYE DISEASE
2011年
12期
926-929
,共4页
近视%激光上皮下角膜磨镶术%角膜浑浊%丝裂霉素C
近視%激光上皮下角膜磨鑲術%角膜渾濁%絲裂黴素C
근시%격광상피하각막마양술%각막혼탁%사렬매소C
Myopia%LASEK%Haze%Mitomycin C
目的 探讨0.01％丝裂霉素C在LASEK术中预防术后haze形成的效果.方法 随机对照的前瞻性临床研究.接受LASEK手术的137例,随机分为两组:对照组69例(137眼)术中用0.02％丝裂霉素C,观察组68例(136眼)术中用0.01％丝裂霉素C,分别浸润切削基质面.观察术后1个月、3个月、6个月时视力、屈光状态、haze形成情况及并发症.结果 两组术后2周裸眼视力大部分达到或接近术前最佳矫正视力,术后6个月视力恢复情况符合美国FDA关于屈光手术有效性和安全性的评价标准.两组间在相同随访时间haze的发生情况差别无统计学意义.按照切削深度选择MMC作用时间后,在切削深度相同时,两组间haze出现情况差别无统计学意义.结论 LASEK术中应用0.01％ MMC并根据切削深度选择作用时间能有效地抑制haze的形成.
目的 探討0.01％絲裂黴素C在LASEK術中預防術後haze形成的效果.方法 隨機對照的前瞻性臨床研究.接受LASEK手術的137例,隨機分為兩組:對照組69例(137眼)術中用0.02％絲裂黴素C,觀察組68例(136眼)術中用0.01％絲裂黴素C,分彆浸潤切削基質麵.觀察術後1箇月、3箇月、6箇月時視力、屈光狀態、haze形成情況及併髮癥.結果 兩組術後2週裸眼視力大部分達到或接近術前最佳矯正視力,術後6箇月視力恢複情況符閤美國FDA關于屈光手術有效性和安全性的評價標準.兩組間在相同隨訪時間haze的髮生情況差彆無統計學意義.按照切削深度選擇MMC作用時間後,在切削深度相同時,兩組間haze齣現情況差彆無統計學意義.結論 LASEK術中應用0.01％ MMC併根據切削深度選擇作用時間能有效地抑製haze的形成.
목적 탐토0.01％사렬매소C재LASEK술중예방술후haze형성적효과.방법 수궤대조적전첨성림상연구.접수LASEK수술적137례,수궤분위량조:대조조69례(137안)술중용0.02％사렬매소C,관찰조68례(136안)술중용0.01％사렬매소C,분별침윤절삭기질면.관찰술후1개월、3개월、6개월시시력、굴광상태、haze형성정황급병발증.결과 량조술후2주라안시력대부분체도혹접근술전최가교정시력,술후6개월시력회복정황부합미국FDA관우굴광수술유효성화안전성적평개표준.량조간재상동수방시간haze적발생정황차별무통계학의의.안조절삭심도선택MMC작용시간후,재절삭심도상동시,량조간haze출현정황차별무통계학의의.결론 LASEK술중응용0.01％ MMC병근거절삭심도선택작용시간능유효지억제haze적형성.
Objective To investigate the effects of 0.01％ Mitomycin-C on preventing corneal haze after laser epithelial keratectomileusis(LASEK).Methods Perspective randomized case-control study was done.137 cases accepted LASEK were randomly divided into two groups,the control group which included 69 cases ( 137 eyes)were treated with 0.02％ mltomycin C,the study group which included 68 cases ( 136eyes) were treated with 0.01％ mitomycin C intraoperation respectively.And the applied time was chosen according to ablation depth.The postoperative uncorrected visual acuity (UCVA),refraction,corneal haze and complications were observed in one month,3 months and 6 months after operation.Results For the most cases,the UCVA was above or equal to preoperative UCVA two weeks postoperatively.The recovery of the visual acuity was accorded to the standard of FDA 6 months after surgery.The haze incidence was not statistically different between the two groups at the same follow-up time.And there was no statistical difference between the two groups with the same corneal ablation depth.Conclusion 0.01 ％ mitomycin C with a chosen application time according to the ablation depth can effectively inhibit corneal haze incidence of LASEK.
