中华耳鼻咽喉头颈外科杂志
中華耳鼻嚥喉頭頸外科雜誌
중화이비인후두경외과잡지
CHINESE JOURNAL OF OTORHINOLARYNGOLOGY HEAD AND NECK SURGERY
2009年
12期
1006-1009
,共4页
王剑%有慧%张振馨%关静%陈兴明%刘剑锋%杨大海%商莹莹%朱莹莹%邹琦娟%高志强%倪道凤
王劍%有慧%張振馨%關靜%陳興明%劉劍鋒%楊大海%商瑩瑩%硃瑩瑩%鄒琦娟%高誌彊%倪道鳳
왕검%유혜%장진형%관정%진흥명%류검봉%양대해%상형형%주형형%추기연%고지강%예도봉
嗅球%年龄组%性别因素%磁共振成像
嗅毬%年齡組%性彆因素%磁共振成像
후구%년령조%성별인소%자공진성상
Olfactory bulb%Age groups%Sex factors%Magnetic resonance imaging
目的 利用磁共振成像(MRI)技术测量健康中老年人嗅球体积在不同年龄、性别和侧别间的差异,为进一步研究嗅觉障碍提供解剖学基础.方法 95例健康中老年受试者,分为50～69岁组和≥70岁2组.所有受试者接受颅脑及嗅球MRI检查,比较嗅球体积在不同年龄、性别和侧别之间的差异.结果 ①50～69岁组的左侧嗅球体积、嗅球总体积和全脑体积(x-±s,以下同)分别为(39.9±8.7)mm~3、(81.7±16.8)mm~3、(1281.9±140.2)cm~3,大于≥70岁组的(34.5±10.4)mm~3、(72.1±19.3)mm~3、(1165.8±165.3)cm~3,差异有统计学意义(t值分别为2.649、2.449、3.516,P值均＜0.05),而右侧嗅球体积及嗅球/脑体积比的差异则无统计学意义(t值分别为1.904、0.616,P值均＞0.05).②男性受试者的左侧嗅球体积、右侧嗅球体积、嗅球总体积、全脑体积以及嗅球/脑体积比大于女性受试者,差异有统计学意义(t值分别为4.461、3.630、4.399、3.800、2.400,P值均＜0.05).③女性受试者、50～69岁受试者、≥70岁受试者左侧嗅球体积小于右侧,差异有统计学意义(t值分别为2.732、2.117、3.516,P值均＜0.05),男性受试者左右侧嗅球体积差异无统计学意义(t=2.649,P=0.110).所有受试者的左侧嗅球/脑体积比均小于右侧嗅球/脑体积比,差异有统计学意义(t=3.183,P=0.002).结论 ①嗅球及颅脑MRI检查可用于嗅球体积研究;②嗅球体积随年龄增加而减小,但嗅球/脑体积比无变化;③男性嗅球体积大于女性嗅球体积;④左侧嗅球体积小于右侧嗅球体积.
目的 利用磁共振成像(MRI)技術測量健康中老年人嗅毬體積在不同年齡、性彆和側彆間的差異,為進一步研究嗅覺障礙提供解剖學基礎.方法 95例健康中老年受試者,分為50～69歲組和≥70歲2組.所有受試者接受顱腦及嗅毬MRI檢查,比較嗅毬體積在不同年齡、性彆和側彆之間的差異.結果 ①50～69歲組的左側嗅毬體積、嗅毬總體積和全腦體積(x-±s,以下同)分彆為(39.9±8.7)mm~3、(81.7±16.8)mm~3、(1281.9±140.2)cm~3,大于≥70歲組的(34.5±10.4)mm~3、(72.1±19.3)mm~3、(1165.8±165.3)cm~3,差異有統計學意義(t值分彆為2.649、2.449、3.516,P值均＜0.05),而右側嗅毬體積及嗅毬/腦體積比的差異則無統計學意義(t值分彆為1.904、0.616,P值均＞0.05).②男性受試者的左側嗅毬體積、右側嗅毬體積、嗅毬總體積、全腦體積以及嗅毬/腦體積比大于女性受試者,差異有統計學意義(t值分彆為4.461、3.630、4.399、3.800、2.400,P值均＜0.05).③女性受試者、50～69歲受試者、≥70歲受試者左側嗅毬體積小于右側,差異有統計學意義(t值分彆為2.732、2.117、3.516,P值均＜0.05),男性受試者左右側嗅毬體積差異無統計學意義(t=2.649,P=0.110).所有受試者的左側嗅毬/腦體積比均小于右側嗅毬/腦體積比,差異有統計學意義(t=3.183,P=0.002).結論 ①嗅毬及顱腦MRI檢查可用于嗅毬體積研究;②嗅毬體積隨年齡增加而減小,但嗅毬/腦體積比無變化;③男性嗅毬體積大于女性嗅毬體積;④左側嗅毬體積小于右側嗅毬體積.
목적 이용자공진성상(MRI)기술측량건강중노년인후구체적재불동년령、성별화측별간적차이,위진일보연구후각장애제공해부학기출.방법 95례건강중노년수시자,분위50～69세조화≥70세2조.소유수시자접수로뇌급후구MRI검사,비교후구체적재불동년령、성별화측별지간적차이.결과 ①50～69세조적좌측후구체적、후구총체적화전뇌체적(x-±s,이하동)분별위(39.9±8.7)mm~3、(81.7±16.8)mm~3、(1281.9±140.2)cm~3,대우≥70세조적(34.5±10.4)mm~3、(72.1±19.3)mm~3、(1165.8±165.3)cm~3,차이유통계학의의(t치분별위2.649、2.449、3.516,P치균＜0.05),이우측후구체적급후구/뇌체적비적차이칙무통계학의의(t치분별위1.904、0.616,P치균＞0.05).②남성수시자적좌측후구체적、우측후구체적、후구총체적、전뇌체적이급후구/뇌체적비대우녀성수시자,차이유통계학의의(t치분별위4.461、3.630、4.399、3.800、2.400,P치균＜0.05).③녀성수시자、50～69세수시자、≥70세수시자좌측후구체적소우우측,차이유통계학의의(t치분별위2.732、2.117、3.516,P치균＜0.05),남성수시자좌우측후구체적차이무통계학의의(t=2.649,P=0.110).소유수시자적좌측후구/뇌체적비균소우우측후구/뇌체적비,차이유통계학의의(t=3.183,P=0.002).결론 ①후구급로뇌MRI검사가용우후구체적연구;②후구체적수년령증가이감소,단후구/뇌체적비무변화;③남성후구체적대우녀성후구체적;④좌측후구체적소우우측후구체적.
Objective To investigate the differences of olfactory bulb(OB)volumes between younger and older,male and female,left-side and right-side in healthy middle and old-aged persons by MRI.Methods Ninety five healthy middle and old-aged volunteers(male:female=45:50)were divided into 2 groups,group one included persons aged from 50 to 69,group two included persons elder than 70.The left-side,right-side and both-side volumes of OB,the volumes of brain and the ratio of OB/brain were measured by MRI.Results(1)The left-side and both-side volumes of OB(x-±s),the volumes of brain [(39.89 ±8.7)mm~3,(81.70 ± 16.8)mm~3 and(1281.86 ± 140.2)cm~3]in 50-69 years old group were respectively larger than those in ≥70 years old group[(34.45 ± 10.4)mm~3,(72.10 ± 19.3)mm~3 and (1165.77 ± 165.3)cm~3],and the differences reached statistical significance(t were respectively 2.649,2.449,3.516,all P＜0.05).There were no significant differences of right-side OB volumes and the ratio of OB/brain between 50-69 years old group and ≥70 years old group(t were respectively 1.904,0.616,each P＞0.05).(2)The male's OB volumes of left-side,right-side and both-side,the brain volumes and the ratio of OB/brain were respectively larger than females',and the differences reached statistical significance(t were respectively 4.461,3.630,4.399,3.800,2.400,all P＜0.05).(3)The right-side OB volumes were larger than left-side's and significant differences were found in female group,50-60 years old group and ≥70 years old group(t were respectively 2.732,2.117,3.516,all P＜0.05).There were no significant differences of OB volumes between left-side and right-side in female(t=2.649,P=0.110).The ratio of right-side OB/brain were larger than the ratio of left-side's and the differences reached statistical significance(t=3.183,P=0.002).Conclusions MRI could be used to measure the volume of OB.The older the people,the smaller the OB volumes.There was no influence of age on the ratio OB/brain.The OB volumes of right-side were larger than those of left-side.The OB volumes of male were larger than those of female.
