中华内科杂志
中華內科雜誌
중화내과잡지
CHINESE JOURNAL OF INTERNAL MEDICINE
2010年
4期
301-304
,共4页
易延静%冉迅%黄晓波%刘雅%张廷杰%欧阳凌云%曾伟%徐俊波%杨雷%刘燕%李秀钧%赵思勤
易延靜%冉迅%黃曉波%劉雅%張廷傑%歐暘凌雲%曾偉%徐俊波%楊雷%劉燕%李秀鈞%趙思勤
역연정%염신%황효파%류아%장정걸%구양릉운%증위%서준파%양뢰%류연%리수균%조사근
中年人%老年人%高血压%糖尿病%糖尿病前期
中年人%老年人%高血壓%糖尿病%糖尿病前期
중년인%노년인%고혈압%당뇨병%당뇨병전기
Middle aged%Aged%Hypertension%Diabetes mellitus%Prediabetic state
目的 探讨成都地区中老年高血压人群糖代谢异常流行状况及影响因素.方法 于2008年采用分层整群抽样的方法,调查成都城乡地区40～79岁中老年人口4685例,进行血压、口服葡萄糖耐量试验(OGTT)等检测,已确诊糖尿病患者只测空腹血糖,开展问卷调查.比较高血压及非高血压人群糖代谢异常患病率,获取中老年高血压人群单纯性糖耐量异常及单纯性负荷后高血糖情况,分析中老年高血压人群糖代谢异常的影响因素.结果 成都地区中老年高血压人群糖代谢异常患病率(53.4%)显著高于非高血压人群(25.1%);若不行OGTT,仅依靠检测空腹血糖,将漏诊中老年高血压人群中72.9%的糖尿病前期患者和54.4%的新诊断糖尿病患者;年龄、一级亲属糖尿病史、超重或肥胖为成都地区中老年男性高血压人群发生糖代谢异常的独立危险因素,体育锻炼、文化程度高为保护因素;年龄、一级亲属糖尿病史、腹型肥胖、高TG血症为成都地区中老年女性高血压人群发生糖代谢异常的独立危险因素.结论 成都地区中老年高血压人群超过半数合并糖代谢异常,需要通过OGTT及时发现这些合并糖代谢异常的患者.适当运动,了解糖尿病相关的保健知识以采取合理的生活方式,干预超重或肥胖、腹型肥胖及高TG血症等代谢性因素,对于减少中老年高血压人群糖代谢异常的发生有着较为重要的作用.
目的 探討成都地區中老年高血壓人群糖代謝異常流行狀況及影響因素.方法 于2008年採用分層整群抽樣的方法,調查成都城鄉地區40～79歲中老年人口4685例,進行血壓、口服葡萄糖耐量試驗(OGTT)等檢測,已確診糖尿病患者隻測空腹血糖,開展問捲調查.比較高血壓及非高血壓人群糖代謝異常患病率,穫取中老年高血壓人群單純性糖耐量異常及單純性負荷後高血糖情況,分析中老年高血壓人群糖代謝異常的影響因素.結果 成都地區中老年高血壓人群糖代謝異常患病率(53.4%)顯著高于非高血壓人群(25.1%);若不行OGTT,僅依靠檢測空腹血糖,將漏診中老年高血壓人群中72.9%的糖尿病前期患者和54.4%的新診斷糖尿病患者;年齡、一級親屬糖尿病史、超重或肥胖為成都地區中老年男性高血壓人群髮生糖代謝異常的獨立危險因素,體育鍛煉、文化程度高為保護因素;年齡、一級親屬糖尿病史、腹型肥胖、高TG血癥為成都地區中老年女性高血壓人群髮生糖代謝異常的獨立危險因素.結論 成都地區中老年高血壓人群超過半數閤併糖代謝異常,需要通過OGTT及時髮現這些閤併糖代謝異常的患者.適噹運動,瞭解糖尿病相關的保健知識以採取閤理的生活方式,榦預超重或肥胖、腹型肥胖及高TG血癥等代謝性因素,對于減少中老年高血壓人群糖代謝異常的髮生有著較為重要的作用.
목적 탐토성도지구중노년고혈압인군당대사이상류행상황급영향인소.방법 우2008년채용분층정군추양적방법,조사성도성향지구40～79세중노년인구4685례,진행혈압、구복포도당내량시험(OGTT)등검측,이학진당뇨병환자지측공복혈당,개전문권조사.비교고혈압급비고혈압인군당대사이상환병솔,획취중노년고혈압인군단순성당내량이상급단순성부하후고혈당정황,분석중노년고혈압인군당대사이상적영향인소.결과 성도지구중노년고혈압인군당대사이상환병솔(53.4%)현저고우비고혈압인군(25.1%);약불행OGTT,부의고검측공복혈당,장루진중노년고혈압인군중72.9%적당뇨병전기환자화54.4%적신진단당뇨병환자;년령、일급친속당뇨병사、초중혹비반위성도지구중노년남성고혈압인군발생당대사이상적독립위험인소,체육단련、문화정도고위보호인소;년령、일급친속당뇨병사、복형비반、고TG혈증위성도지구중노년녀성고혈압인군발생당대사이상적독립위험인소.결론 성도지구중노년고혈압인군초과반수합병당대사이상,수요통과OGTT급시발현저사합병당대사이상적환자.괄당운동,료해당뇨병상관적보건지식이채취합리적생활방식,간예초중혹비반、복형비반급고TG혈증등대사성인소,대우감소중노년고혈압인군당대사이상적발생유착교위중요적작용.
Objective To explore the epidemiological status of abnormal glucose metabolism and its influential factors among middle and aged population with hypertension in Chengdu area. Methods In 2008, after adopting the methods of stratified cluster sampling, the authors investigated 4685 subjects of the middle and aged population between the age of 40-79 in Chengdu urban and rural area by checking blood pressure and oral glucose tolerance test (OGTY). Patients with previously known diabetes mellitus (DM) were only asked to perform fasting glucose and to carry out a questionnaire. Comparison of the prevalence rates of abnormal glucose metabolism in hypertensive and non-hypertensive subjects was carried out. The prevalence rates of isolated impaired glucose tolerance (I-IGT) and isolated postprandial hyperglycemia (IPH) among middle and aged subjects with hypertension were acquired and the influential factors of abnormal glucose metabolism among middle and aged subjects with hypertension were analyzed. Results The prevalence rate of abnormal glucose metabolism in the hypertensive subjects was obviously higher than that in the non-hypertensive subjects; without using OGTT, 72.9% of the pre-diubetic and 54. 4% of the new diagnosed DM patients would remain undiagnosed if fasting plasma glucose detection was used alone. Age, diabetic history of first degree relatives ,overweight or obesity were the risk factors for the development of abnormal glucose metabolism among middle and aged male subjects with hypertension in Chengdu area. Exercise training and high education level were the protective factors. Age, diabetic history of first degree relatives,abdominal obesity and hypertriglyceridemia were the risk factors for the development of abnormal glucose metabolism among middle and aged female subjects with hypertension in Chengdu area. Conclusions More than 50% of middle and aged subjects with hypertension in Chengdu area has accompanying abnormal glucose metabolism. OGTT easily discloses the abnormal status and should be a routine procedure in the diagnosis of pre-diabetes or DM in such population. Appropriate exercise, learning diabetes-related knowledge to take reasonable lifestyle, and intervention of metabolic factors such as overweight or obesity are advised. Abdominal obesity and hypertriglyceridemia play important roles in leading to abnormal glucose metabolism among middle and aged population with hypertension.
