国际医药卫生导报
國際醫藥衛生導報
국제의약위생도보
INTERNATIONAL MEDICINE & HEALTH GUIDANCE NEWS
2012年
11期
1583-1585
,共3页
乳酶生片%复发性念珠菌性阴道炎
乳酶生片%複髮性唸珠菌性陰道炎
유매생편%복발성념주균성음도염
Lactasin tablet%Recurrent vulvovaginal candidiasis
目的 观察乳酶生片联合达克宁栓治疗复发性念珠菌性阴道炎疗效.方法 300例复发性念珠菌性阴道炎患者随机、单盲分为治疗组150例和对照组150例,对照组采用达克宁栓200 mg,阴道上药,每晚一次,共用7天.治疗组在对照组的基础上加用乳酶生片0.6 g,每晚一次,共用7～10天.两组用药均每月重复一次,连用3个月.分别于治疗前,治疗后1个月、2个月、3个月进行疗效观察,比较复发情况.结果 治疗组总有效率为94.7％,治疗3个月后复发率为5.97％；对照组总有效率为85.3％,治疗3个月后复发率为19.04％,治疗组疗效明显优于对照组(P＜0.01),治疗组各症状复发明显少于对照组(P＜0.05)且治疗组复发率明显低于对照组(P＜0.0l).结论 乳酶生片与达克宁栓合用治疗复发性念珠菌性阴道炎效果良好,可明显减少复发.
目的 觀察乳酶生片聯閤達剋寧栓治療複髮性唸珠菌性陰道炎療效.方法 300例複髮性唸珠菌性陰道炎患者隨機、單盲分為治療組150例和對照組150例,對照組採用達剋寧栓200 mg,陰道上藥,每晚一次,共用7天.治療組在對照組的基礎上加用乳酶生片0.6 g,每晚一次,共用7～10天.兩組用藥均每月重複一次,連用3箇月.分彆于治療前,治療後1箇月、2箇月、3箇月進行療效觀察,比較複髮情況.結果 治療組總有效率為94.7％,治療3箇月後複髮率為5.97％；對照組總有效率為85.3％,治療3箇月後複髮率為19.04％,治療組療效明顯優于對照組(P＜0.01),治療組各癥狀複髮明顯少于對照組(P＜0.05)且治療組複髮率明顯低于對照組(P＜0.0l).結論 乳酶生片與達剋寧栓閤用治療複髮性唸珠菌性陰道炎效果良好,可明顯減少複髮.
목적 관찰유매생편연합체극저전치료복발성념주균성음도염료효.방법 300례복발성념주균성음도염환자수궤、단맹분위치료조150례화대조조150례,대조조채용체극저전200 mg,음도상약,매만일차,공용7천.치료조재대조조적기출상가용유매생편0.6 g,매만일차,공용7～10천.량조용약균매월중복일차,련용3개월.분별우치료전,치료후1개월、2개월、3개월진행료효관찰,비교복발정황.결과 치료조총유효솔위94.7％,치료3개월후복발솔위5.97％；대조조총유효솔위85.3％,치료3개월후복발솔위19.04％,치료조료효명현우우대조조(P＜0.01),치료조각증상복발명현소우대조조(P＜0.05)차치료조복발솔명현저우대조조(P＜0.0l).결론 유매생편여체극저전합용치료복발성념주균성음도염효과량호,가명현감소복발.
Objective To observe lactasin tablet combined with miconazole suppository in the treatment of recurrent vulvovaginal candidiasis.Methods 300 patients with recnrrent vulvovaginal candidiasis were randomly and blindly divided into study group and control group,150 for each group.The control group received miconazole vaginal suppository of 200 mg once per night for 7 to 10 days,while the study group received lactasin tablet of 600 mg per night for 7 to 10 days in addition to therapy with vaginal suppository.The same therapy was applied twice monthly in the same groupfor three months.The efficacies were observed in both groups one,two,and three months after treatment; the recurrence rates were compared.Results The study group was superior to the control group in the efficacy ( 94.7％ vs.85.3％ for the total effectiveness rate,5.97％ vs.19.04％ for the recurrence rate 3 months after treatment; P＜ 0.01 ).The rate of symptom recurrence was significantly lower in the study group than in the control group ( P ＜ 0.05 ),and so was the recurrence rate ( P ＜ 0.01 ).Conclusions Lactasin tablet combined with miconazole suppository for reeurrent vulvovaginal candidiasis is efficacious and can significantly reduce recurrence.
