中国医药
中國醫藥
중국의약
CHINA MEDICINE
2012年
2期
146-147
,共2页
头颅亚低温%奥扎格雷%血塞通%急性脑梗死%疗效
頭顱亞低溫%奧扎格雷%血塞通%急性腦梗死%療效
두로아저온%오찰격뢰%혈새통%급성뇌경사%료효
Brain mild hypothermia%Aozhagelei%Xuesaitong%Acute cerebral infarction%Curative effect
目的 观察头颅亚低温联合奥扎格雷和血塞通治疗急性脑梗死的疗效.方法 将84例急性脑梗死患者完全随机分为治疗组和对照组,各42例.治疗组采用头颅亚低温联合奥扎格雷钠注射液80 mg、2次/d静脉滴注和血塞通注射液400 mg、1次/d,对照组采用血塞通注射液400 mg,1次/d静脉滴注,均治疗14 d.比较2组患者的临床疗效、神经功能评分及不良反应情况.结果 治疗组总有效率明显高于对照组[95.2％ (40/42)比80.9％(34/42),P＜0.05],2组治疗后神经功能缺损评分均明显低于治疗前[治疗组(10.9±4.1)分比(33.0±4.8)分,对照组(20.0±5.1)分比(32.9±5.0)分,均P＜0.01],治疗后治疗组与对照组相比神经功能缺损评分明显低于对照组(P＜0.01).2组患者均无明显不良反应发生.结论 头颅亚低温联合奥扎格雷和血塞通治疗急性脑梗死疗效好安全.
目的 觀察頭顱亞低溫聯閤奧扎格雷和血塞通治療急性腦梗死的療效.方法 將84例急性腦梗死患者完全隨機分為治療組和對照組,各42例.治療組採用頭顱亞低溫聯閤奧扎格雷鈉註射液80 mg、2次/d靜脈滴註和血塞通註射液400 mg、1次/d,對照組採用血塞通註射液400 mg,1次/d靜脈滴註,均治療14 d.比較2組患者的臨床療效、神經功能評分及不良反應情況.結果 治療組總有效率明顯高于對照組[95.2％ (40/42)比80.9％(34/42),P＜0.05],2組治療後神經功能缺損評分均明顯低于治療前[治療組(10.9±4.1)分比(33.0±4.8)分,對照組(20.0±5.1)分比(32.9±5.0)分,均P＜0.01],治療後治療組與對照組相比神經功能缺損評分明顯低于對照組(P＜0.01).2組患者均無明顯不良反應髮生.結論 頭顱亞低溫聯閤奧扎格雷和血塞通治療急性腦梗死療效好安全.
목적 관찰두로아저온연합오찰격뢰화혈새통치료급성뇌경사적료효.방법 장84례급성뇌경사환자완전수궤분위치료조화대조조,각42례.치료조채용두로아저온연합오찰격뢰납주사액80 mg、2차/d정맥적주화혈새통주사액400 mg、1차/d,대조조채용혈새통주사액400 mg,1차/d정맥적주,균치료14 d.비교2조환자적림상료효、신경공능평분급불량반응정황.결과 치료조총유효솔명현고우대조조[95.2％ (40/42)비80.9％(34/42),P＜0.05],2조치료후신경공능결손평분균명현저우치료전[치료조(10.9±4.1)분비(33.0±4.8)분,대조조(20.0±5.1)분비(32.9±5.0)분,균P＜0.01],치료후치료조여대조조상비신경공능결손평분명현저우대조조(P＜0.01).2조환자균무명현불량반응발생.결론 두로아저온연합오찰격뢰화혈새통치료급성뇌경사료효호안전.
Objective To investigate the curative effects of brain mild hypothermia combined with aozhagelei and xuesaitong on acute cerebral infarction.Methods A total of 84 patients with acute cerebral infarction were randomly assigned to treatment group (42 patients) and control group (42 patients).Brain mild hypothermia was combined with aozhageleina injection 80 mg + saline 250 ml twice a day and xuesaitong 400 mg + saline 250 ml once a day used for intravenous drip for 14 days in the treatment group; xuesaitong 400 mg + saline 250 ml were used for intravenous drip once a day for 14 days in the control group.Other measures of symptomatic therapy in both groups were the same.Results The total effective rate of 95.2％ in treatment group was significantly superior to that of 80.9％ in control group (P ＜ 0.05).The score of neurological deficits was significantly decreased in the treatment group after 14 days compared with the control group ( P ＜ 0.01 ).There were no obvious side effects in the two groups.Conclusion The curative effect of brain mild hypothermia combined with aozhagelei and xuesaitong on acute cerebral infarction is feasible and safe.
