CAJ | 학술논문

以邻苯二乙醚为主要原料,经混酸硝化后催化加氢还原,得中间体对氨基邻苯二乙醚,再与氯甲酸异丙酯缩合,得到乙霉威.结果表明,催化加氢还原的最佳条件:反应温度90 ℃,催化剂用量为反应物质量的3%,压力1.5 MPa,反应时间3 h;缩合反应的最佳条件:以三乙胺为缚酸剂,溶剂甲苯与反应物的质量比为2.1:1,对氨基邻苯二乙醚与氯甲酸异丙酯的摩尔比为1:1.3,反应时间0.5 h.在较佳的反应条件下,乙霉威的总收率≥80.38%,含量≥98%.
이린분이을미위주요원료,경혼산초화후최화가경환원,득중간체대안기린분이을미,재여록갑산이병지축합,득도을매위.결과표명,최화가경환원적최가조건:반응온도90 ℃,최화제용량위반응물질량적3%,압력1.5 MPa,반응시간3 h;축합반응적최가조건:이삼을알위박산제,용제갑분여반응물적질량비위2.1:1,대안기린분이을미여록갑산이병지적마이비위1:1.3,반응시간0.5 h.재교가적반응조건하,을매위적총수솔≥80.38%,함량≥98%.
Diethofencarb was synthesized from 1,2-diethoxybenzene by nitrification,reduction and condensation reaction.The optimum synthetic conditions:reaction temperature is 90 ℃,amount of catalyst is 3%,reaction pressure is 1.5 MPa and reaction time is 3 h.The optimum reaction conditions in condensation reaction were also obtained:with triethylamine as acid binding 0.5 h.The total yield of diethofencarb is above 80.38%,its purity is above 98%.