CAJ | 학술논문

通过统计草鱼(Ctenopharyngodon idellus)外周血红细胞的微核率和斑马鱼(Brachydanio redo)胚胎致畸率,研究了氰戊菊酯对鱼类的致突变效应.结果显示:氰戊菊酯对1龄草鱼的96 h半致死浓度(LC50)为60.62 μg/L;1.2 μg/L以上的氰戊菊酯能显著提高草鱼的微核率、核异常率以及总核异常率,三者的变化趋势均是随着暴露时间的延长先升高,达到峰值后再缓慢下降;微核率与空白对照组比较呈显著性差异.表明氰戊菊酯对草鱼染色体畸变有明显影响.在2～32 μg/L的氰戊菊酯中,随着浓度的升高,斑马鱼的胚胎死亡率升高、出膜率降低、80%胚胎出膜时间延长,仔鱼畸形率升高,说明氰戊菊酯对斑马鱼胚胎及仔鱼有致畸作用.
통과통계초어(Ctenopharyngodon idellus)외주혈홍세포적미핵솔화반마어(Brachydanio redo)배태치기솔,연구료청무국지대어류적치돌변효응.결과현시:청무국지대1령초어적96 h반치사농도(LC50)위60.62 μg/L;1.2 μg/L이상적청무국지능현저제고초어적미핵솔、핵이상솔이급총핵이상솔,삼자적변화추세균시수착폭로시간적연장선승고,체도봉치후재완만하강;미핵솔여공백대조조비교정현저성차이.표명청무국지대초어염색체기변유명현영향.재2～32 μg/L적청무국지중,수착농도적승고,반마어적배태사망솔승고、출막솔강저、80%배태출막시간연장,자어기형솔승고,설명청무국지대반마어배태급자어유치기작용.
The effect of mutagenesis of fenvalerat on fish had been studied by micronucleus test on grass carp and zebrafish embryo test.The results indicated that the 96 h semi-lethal concentration of fenvalerat was 60.62 μg/L.When the fenvalerat was above 1.2 μg/L,it could significantly increased the micronucleus rate,nuclear abnormities rate and the total nuclear anomalies rate.All the rates increased before the peak,and then declined slowly.The micrenuclei rate had significant difference with control group.The results indicated that fenvalerat had significant effect on chromosomal aberration of grass carp.Zebrafish embryo test showed that:when the concentration of fenvalerat was between 2 peJl.and 32 μg/L,the lethal rates of zebrafish embryo declined and hatching rates increased as the dose of fenvalerat increased.And 80% hatchingtime prolonged.Some larval appeared deformity phenomenon in the high concentration of fenvalerat.This suggested that fenvalerat had teratogenicity for embryo and larval of zebrafish.