CAJ | 학술논문

目的了解各年龄段非瓣膜病心房纤颤(NVAF)患者的病因分布,脑卒中发生率以及心房纤颤类型对脑卒中的影响.方法对329例NVAF患者进行随访调查.按年龄分为A组(≤60岁)、B组(61～70岁)、C组(71～80岁)、D组(>80岁)4组,调查各组的临床特点及预后.结果 NVAF各年龄组患者的首要病因均为冠心病;A、B组的甲状腺机能亢进性心脏病的病因构成均明显高于C、D组(P＜0.05).各年龄组患者的脑卒中发生率分别为21.79%、26.61%、35.85%和50.00%,脑卒中发生率有随年龄增长而增加的趋势(P＜0.05).对不同NVAF患者的缺血性脑卒中发生率按年龄因素进行分层分析,仅A组有统计学意义(P＜0.05).结论冠心病是NVAF各年龄组的首要病因;脑卒中的发生随年龄的增加而增长;持续性和阵发性心房纤颤类型在年龄≤60岁的年龄组患者脑卒中发生率间有明显差异.
목적 료해각년령단비판막병심방섬전(NVAF)환자적병인분포,뇌졸중발생솔이급심방섬전류형대뇌졸중적영향.방법 대329례NVAF환자진행수방조사.안년령분위A조(≤60세)、B조(61～70세)、C조(71～80세)、D조(>80세)4조,조사각조적림상특점급예후.결과 NVAF각년령조환자적수요병인균위관심병;A、B조적갑상선궤능항진성심장병적병인구성균명현고우C、D조(P＜0.05).각년령조환자적뇌졸중발생솔분별위21.79%、26.61%、35.85%화50.00%,뇌졸중발생솔유수년령증장이증가적추세(P＜0.05).대불동NVAF환자적결혈성뇌졸중발생솔안년령인소진행분층분석,부A조유통계학의의(P＜0.05).결론 관심병시NVAF각년령조적수요병인;뇌졸중적발생수년령적증가이증장;지속성화진발성심방섬전류형재년령≤60세적년령조환자뇌졸중발생솔간유명현차이.
Objective To explore the incidence of stroke and relative factors in patients of different age groups with non-valvular atrial fibrillation(NVAF).Methods Totally 329 NVAF patients admitted in our hospital from January 1999 to December 2001 were divided into four groups according to their ages: group A (≤60 years),group B (61 - 70 years),group C (71 - 80 years),and group D (﹥80 years).The etiology,clinical features and prognosis of all four groups were investigated and summarized.Results Coronary heart disease (CHD) remained the leading cause in all groups.Hyperthyroid heart disease accounted a significantly higher proportion in groups A and B than in groups C and D(P＜0.05).The incidence of stroke was 21.79%,26.61%,35.85%,and 50.00% in groups A,B,C,and D,respectively.It increased along with the increase of age (P＜0.05).The incidence of ischemic stroke were significantly different among different NVAF type strata (P＜0.05) in group A,while no such difference was observed in other three groups (P＞0.05).Conclusion CHD is the main cause of NVAF.Incidence of stroke increases with aging.The incidences of Persistent and paroxysmal atrial fibrillation only differ among NVAF patients younger than 60 years.