中华内分泌外科杂志
中華內分泌外科雜誌
중화내분비외과잡지
CHINESE JOURNAL OF ENDOCRINE SURGERY
2011年
2期
106-108
,共3页
余明%黄亮%涂群飞%周卫%苏雄飞
餘明%黃亮%塗群飛%週衛%囌雄飛
여명%황량%도군비%주위%소웅비
分化型甲状腺癌%局部晚期
分化型甲狀腺癌%跼部晚期
분화형갑상선암%국부만기
Differentiated thyroid tumor%Local advanced tumor
目的 探讨局部晚期分化型甲状腺癌的临床特点及治疗方法,以期提高患者的生存时间及生存质量.方法 回顾性分析南昌大学第二附属医院1996年1月至2005年12月治疗的23例局部晚期分化型甲状腺癌的临床病理资料,包括年龄、病理类型、肿瘤局部侵犯情况、手术方案、术后并发症及生存期等.根据随访结果进行疗效及预后分析.结果甲状腺乳头状癌15例,滤泡状癌6例,乳头滤泡状癌2例.肿瘤局部侵犯喉返神经8例,侵犯气管12例,侵犯气管及食道3例,合并侵犯颈前肌群8例.23例均行手术治疗,其中肿瘤根治6例,肿瘤剔除14例,姑息性切除3例(2例术后加行局部放疗).全组1、3、5年总生存率为91.3%(21/23)、82.6%(19/23)、60.8%(14/23).其中根治组和剔除组预后明显好于姑息组.结论 局部晚期分化型甲状腺癌手术治疗后仍能取得较好疗效,重视保护局部器官功能是提高术后生存质量的保证.
目的 探討跼部晚期分化型甲狀腺癌的臨床特點及治療方法,以期提高患者的生存時間及生存質量.方法 迴顧性分析南昌大學第二附屬醫院1996年1月至2005年12月治療的23例跼部晚期分化型甲狀腺癌的臨床病理資料,包括年齡、病理類型、腫瘤跼部侵犯情況、手術方案、術後併髮癥及生存期等.根據隨訪結果進行療效及預後分析.結果甲狀腺乳頭狀癌15例,濾泡狀癌6例,乳頭濾泡狀癌2例.腫瘤跼部侵犯喉返神經8例,侵犯氣管12例,侵犯氣管及食道3例,閤併侵犯頸前肌群8例.23例均行手術治療,其中腫瘤根治6例,腫瘤剔除14例,姑息性切除3例(2例術後加行跼部放療).全組1、3、5年總生存率為91.3%(21/23)、82.6%(19/23)、60.8%(14/23).其中根治組和剔除組預後明顯好于姑息組.結論 跼部晚期分化型甲狀腺癌手術治療後仍能取得較好療效,重視保護跼部器官功能是提高術後生存質量的保證.
목적 탐토국부만기분화형갑상선암적림상특점급치료방법,이기제고환자적생존시간급생존질량.방법 회고성분석남창대학제이부속의원1996년1월지2005년12월치료적23례국부만기분화형갑상선암적림상병리자료,포괄년령、병리류형、종류국부침범정황、수술방안、술후병발증급생존기등.근거수방결과진행료효급예후분석.결과갑상선유두상암15례,려포상암6례,유두려포상암2례.종류국부침범후반신경8례,침범기관12례,침범기관급식도3례,합병침범경전기군8례.23례균행수술치료,기중종류근치6례,종류척제14례,고식성절제3례(2례술후가행국부방료).전조1、3、5년총생존솔위91.3%(21/23)、82.6%(19/23)、60.8%(14/23).기중근치조화척제조예후명현호우고식조.결론 국부만기분화형갑상선암수술치료후잉능취득교호료효,중시보호국부기관공능시제고술후생존질량적보증.
Objective To investigate clinieopathologic characteristics and therapy of local advanced welldifferentiated thyroid carcinoma.Methods Data of 23 cases of advanced well-differentiated thyroid carcinoma treated from Jan.1996 to Dec.2005 were retrospectively reviewed.The data included age,pathologic type,local invasion,operative plan,postoperative complications and survival duration.Results Histology showed there were 15 cases of papillary carcinoma,6 ca8es of follicular carcinoma,and 2 cases of papiIlary follicular carcinoma.8 cases had local invasion into recurrent laryngeal nerve,12 cases had invasion into trachea,3 cases had trachea and esophagus invasion,and 8 cases had suprahyoid muscle invasion.All the 23 cases underwent resection procedure.According to surgical procedure,they were divided into radical resection group(n=6),tumor resection group(n=14)and tumor debulking group(n=3).2 cases received radiotherapy after thyroidectomy in tumor debulking group.All patients were followed up.Overall survival rate after 1 year,3 years and 5 years Was 91.3%(21/23),82.6%(19/23),and 60.8%(14/23)respectively.Prognosis of radical tumor removal group and tumor resection group was obviously better than that of tumor debulking group.Conclusions Prognosis is good for local advanced well-differentiated thyroid carcinoma patients receiving resection.Protection of local organ function Can enhance postoperative life quality.
