中华老年医学杂志
中華老年醫學雜誌
중화노년의학잡지
Chinese Journal of Geriatrics
2009年
4期
290-293
,共4页
马传栋%陈小松%柳光宇%狄根红%吴炅%陆劲松%杨文涛%韩企夏%邵志敏%沈镇宙%沈坤炜
馬傳棟%陳小鬆%柳光宇%狄根紅%吳炅%陸勁鬆%楊文濤%韓企夏%邵誌敏%瀋鎮宙%瀋坤煒
마전동%진소송%류광우%적근홍%오경%륙경송%양문도%한기하%소지민%침진주%침곤위
乳腺肿瘤%化学疗法,辅助
乳腺腫瘤%化學療法,輔助
유선종류%화학요법,보조
Breast neoplasms%Chemotherapy,adjuvant
目的 探讨65岁以上乳腺癌患者接受术后辅助化疗的影响因素. 方法 采用χ2检验和Logistic回归分析方法对590例65岁以上浸润性乳腺癌患者术后辅助化疗的影响因素进行分析. 结果 全组接受术后辅助化疗者231例,占39.15%.结果表明,并存糖尿病、年龄、手术方式及肿瘤的病理生物学特征对患者接受术后辅助化疗有影响(χ2值分别为4.49、88.27、23.49及9.40,均为P<0.05).Logistic回归分析结果显示.年龄、术后病理肿瘤最大径(pT)、术后病理淋巴结状况(pN)、雌激素受体(ER)对接受术后辅助化疗有影响(χ2值分别为68.857、15.284、43.540、7.009,均为P<0.01).淋巴结阳性激素受体阴性的患者中44例(66.7%)接受了术后辅助化疗. 结论 肿瘤大小、淋巴结状况、激素受体状况和年龄是老年乳腺癌患者接受术后辅助化疗的独立预测因素.
目的 探討65歲以上乳腺癌患者接受術後輔助化療的影響因素. 方法 採用χ2檢驗和Logistic迴歸分析方法對590例65歲以上浸潤性乳腺癌患者術後輔助化療的影響因素進行分析. 結果 全組接受術後輔助化療者231例,佔39.15%.結果錶明,併存糖尿病、年齡、手術方式及腫瘤的病理生物學特徵對患者接受術後輔助化療有影響(χ2值分彆為4.49、88.27、23.49及9.40,均為P<0.05).Logistic迴歸分析結果顯示.年齡、術後病理腫瘤最大徑(pT)、術後病理淋巴結狀況(pN)、雌激素受體(ER)對接受術後輔助化療有影響(χ2值分彆為68.857、15.284、43.540、7.009,均為P<0.01).淋巴結暘性激素受體陰性的患者中44例(66.7%)接受瞭術後輔助化療. 結論 腫瘤大小、淋巴結狀況、激素受體狀況和年齡是老年乳腺癌患者接受術後輔助化療的獨立預測因素.
목적 탐토65세이상유선암환자접수술후보조화료적영향인소. 방법 채용χ2검험화Logistic회귀분석방법대590례65세이상침윤성유선암환자술후보조화료적영향인소진행분석. 결과 전조접수술후보조화료자231례,점39.15%.결과표명,병존당뇨병、년령、수술방식급종류적병리생물학특정대환자접수술후보조화료유영향(χ2치분별위4.49、88.27、23.49급9.40,균위P<0.05).Logistic회귀분석결과현시.년령、술후병리종류최대경(pT)、술후병리림파결상황(pN)、자격소수체(ER)대접수술후보조화료유영향(χ2치분별위68.857、15.284、43.540、7.009,균위P<0.01).림파결양성격소수체음성적환자중44례(66.7%)접수료술후보조화료. 결론 종류대소、림파결상황、격소수체상황화년령시노년유선암환자접수술후보조화료적독립예측인소.
Objective To explore the influencing factors for postoperative adjuvant chemotherapy effects in elderly patients with breast cancer. Methods Five hundred and ninety female patients aged 65 years or older with invasive breast cancer were treated in our hospital, and the influencing factors for postoperative adjuvant chemotherapy effects were analyzed by chi-square test and logistic regression. Results Two hundred and thirty-one (39.2%) patients received postoperative adjuvant chemotherapy. The results showed that diabetes, age, patterns of operation and pathological characteristics of tumor had significant influences on postoperative adjuvant chemotherapy effects (χ2=4.49,88. 27,23.49 and 9.40, all P<0.05). Logistic regression analysis showed that age, tumor size, lymph node status(pN) and estrogen receptor (ER) status were related to postoperative adjuvant chemotherapy effects(χ2=68.857,15. 284,43. 540 and 7.009 ,all P<0.01). Forty-four patients (66.7%) with pN(+)/ER(-) received adjuvant chemotherapy. Conclusions Age, tumor size, lymph node status and ER status were independent predictive factors for postoperative adjuvant chemotherapy effects in elderly patients with breast cancer.
