CAJ | 학술논문

目的总结咪达唑仑口服镇静术对口腔诊疗不配合的儿童患者的临床效果,探讨年龄因素对咪达唑仑治疗效果和安全性的影响.方法选取109例对口腔诊疗不配合的儿童患者,在门诊环境下实施咪达唑仑口服镇静术辅助诊疗,给药剂量为0.50～0.75 mg/kg,记录各项评价指标并对≤3岁组(40例)和＞3岁组(69例)的治疗效果和安全性进行分析、比较.结果镇静治疗总成功率为71%(77/109),≤3岁组治疗成功率[58%(23/40)]显著低于3岁以上组[78%(54/69)](x2=5.26,P＜0.05);总不良反应发生率为17%(19/109),≤3岁组不良反应发生率[28%(11/40)]显著高于3岁以上组[12%(8/69)],x2=4.24,P＜0.05.结论咪达唑仑口服镇静术对3岁以上患者治疗效果好,不良反应相对少;口服咪达唑仑0.50～0.75 mg/kg的剂量范围安全有效.
목적 총결미체서륜구복진정술대구강진료불배합적인동환자적림상효과,탐토년령인소대미체서륜치료효과화안전성적영향.방법 선취109례대구강진료불배합적인동환자,재문진배경하실시미체서륜구복진정술보조진료,급약제량위0.50～0.75 mg/kg,기록각항평개지표병대≤3세조(40례)화＞3세조(69례)적치료효과화안전성진행분석、비교.결과 진정치료총성공솔위71%(77/109),≤3세조치료성공솔[58%(23/40)]현저저우3세이상조[78%(54/69)](x2=5.26,P＜0.05);총불량반응발생솔위17%(19/109),≤3세조불량반응발생솔[28%(11/40)]현저고우3세이상조[12%(8/69)],x2=4.24,P＜0.05.결론 미체서륜구복진정술대3세이상환자치료효과호,불량반응상대소;구복미체서륜0.50～0.75 mg/kg적제량범위안전유효.
Objective To summarize the effect of oral midazolam sedation in a group of uncooperative patients in pediatric dentistry and analyze the influence of age on treatment results and safety.Methods Oral midazolam conscious sedation (dosages range: 0. 50-0. 75 mg/kg) was applied to 109 uncooperative pediatric patients in outpatient department. The patients were divided into two age groups:group A (under 3 years) and group B (over 3 years). Treatment results and safety were statistically analyzed. Results The mean success rate was 71% (77/109), which was higher in group B[78%(54/69)]than in group A[58% (23/40)]. The incidence of adverse reactions was 17% (19/109),which was higher in group A [28% (11/40)] than in group B [12% ( 8/69 )]. Conclusions Oral midazolam conscious sedation at a dosage range of 0. 50-0. 75 mg/kg is more effective and safe in pediatric dental patients over 3 years of age.