中国医师进修杂志
中國醫師進脩雜誌
중국의사진수잡지
CHINESE JOURNAL OF POSTGRADUATES OF MEDICINE
2012年
10期
25-27
,共3页
张玲玲%陆以霞%李强%祝喜萍
張玲玲%陸以霞%李彊%祝喜萍
장령령%륙이하%리강%축희평
结肠疾病%结直肠肿瘤%免疫粪潜血试验
結腸疾病%結直腸腫瘤%免疫糞潛血試驗
결장질병%결직장종류%면역분잠혈시험
Colonic diseases%Colorectal neoplasms%Immunochemical fecal occult blood test
目的 探讨免疫粪潜血试验对诊断大肠疾病的临床意义.方法 选择2008年1月至2011年8月行免疫粪潜血试验及化学粪潜血试验患者共251例,并行大肠镜检查结合病理确诊.结果 免疫粪潜血试验和化学粪潜血试验对结直肠癌的阳性率分别为100.0% (57/57)和84.2% (48/57),差异有统计学意义(P<0.05);大肠息肉分别为38.6% (32/83)和10.8% (9/83),差异有统计学意义(P<0.05);炎症性肠病分别为100.0% (31/31)和80.6% (25/31),差异无统计学意义(P>0.05);非特异性肠炎分别为86.8%(33/38)和73.7%(28/38),差异无统计学意义(P> 0.05);正常大肠分别为2.4% (1/42)和19.0% (8/42),差异有统计学意义(P<0.05).结论 免疫粪潜血试验对诊断结直肠癌和大肠息肉优于化学粪潜血试验,假阳性率明显降低.
目的 探討免疫糞潛血試驗對診斷大腸疾病的臨床意義.方法 選擇2008年1月至2011年8月行免疫糞潛血試驗及化學糞潛血試驗患者共251例,併行大腸鏡檢查結閤病理確診.結果 免疫糞潛血試驗和化學糞潛血試驗對結直腸癌的暘性率分彆為100.0% (57/57)和84.2% (48/57),差異有統計學意義(P<0.05);大腸息肉分彆為38.6% (32/83)和10.8% (9/83),差異有統計學意義(P<0.05);炎癥性腸病分彆為100.0% (31/31)和80.6% (25/31),差異無統計學意義(P>0.05);非特異性腸炎分彆為86.8%(33/38)和73.7%(28/38),差異無統計學意義(P> 0.05);正常大腸分彆為2.4% (1/42)和19.0% (8/42),差異有統計學意義(P<0.05).結論 免疫糞潛血試驗對診斷結直腸癌和大腸息肉優于化學糞潛血試驗,假暘性率明顯降低.
목적 탐토면역분잠혈시험대진단대장질병적림상의의.방법 선택2008년1월지2011년8월행면역분잠혈시험급화학분잠혈시험환자공251례,병행대장경검사결합병리학진.결과 면역분잠혈시험화화학분잠혈시험대결직장암적양성솔분별위100.0% (57/57)화84.2% (48/57),차이유통계학의의(P<0.05);대장식육분별위38.6% (32/83)화10.8% (9/83),차이유통계학의의(P<0.05);염증성장병분별위100.0% (31/31)화80.6% (25/31),차이무통계학의의(P>0.05);비특이성장염분별위86.8%(33/38)화73.7%(28/38),차이무통계학의의(P> 0.05);정상대장분별위2.4% (1/42)화19.0% (8/42),차이유통계학의의(P<0.05).결론 면역분잠혈시험대진단결직장암화대장식육우우화학분잠혈시험,가양성솔명현강저.
Objective To discuss the value of immunochemical fecal occult blood test (IFOBT) in diagnosis of colorectal diseases.Methods Two hundred and fifty-one patients who taken IFOBT and chemical fecal occult blood test (CFOBT) from January 2008 to August 2011 were enrolled in this study.They were definitely diagnosed by total colonoscopy combined with pathology.Results The positive rate of IFOBT and CFOBT in colorectal cancer patients was 100.0% (57/57) and 84.2% (48/57),there was significant difference (P < 0.05).The positive rate of IFOBT and CFOBT in colorectal polyp patients was 38.6% (32/83) and 10.8%(9/83 ),there was significant difference(P < 0.05 ).The positive rate of IFOBT and CFOBT in inflammatory bowel disease patients was 100.0% (31/31) and 80.6% (25/31),there was no significant difference (P > 0.05).The positive rate of IFOBT and CFOBT in non-specific enteritis patients were 86.8% (33/38) and 73.7% (28/38),there was no significant difference (P > 0.05 ).The positive rate of IFOBT and CFOBT in normal colorectal cases was 2.4% (1/42) and 19.0% (8/42),there was siguificant difference (P < 0.05).Conclusions IFOBT is better than CFOBT in diagnosis of colorectal cancer and colorectal polyp.IFOBT has lower false positive rate.