中华儿科杂志
中華兒科雜誌
중화인과잡지
Chinese Journal of Pediatrics
2009年
11期
871-873
,共3页
梅毒%先天性%婴儿%临床
梅毒%先天性%嬰兒%臨床
매독%선천성%영인%림상
Syphilis,congenital%Infant%Clinical
目的 为了解3个月以下幼婴先天性梅毒(CS)的临床特点及误诊情况.方法 收集我院1997年1月-2007年5月确诊为先天性梅毒的3个月以下幼婴121例,将临床表现、实验室检查及治疗情况进行回顾性分析.结果 3个月以下幼婴先天性梅毒的临床表现多样,累及皮肤、呼吸、消化、血液、神经、骨骼等多系统,121例中白细胞增高89.3%,皮肤损害59.5%,肝脏肿大56.2%,脾肿大41.3%,贫血38.8%,发热28.9%,病理性黄疸24.0%,出生后生长发育迟缓12.4%,骨骼损害54.3%等;误诊率17.4%,误诊疾病达10种.结论 3个月以下幼婴先天性梅毒的临床表现复杂多变,缺乏特异性,易被误诊,需要临床医师提高警惕;恢复婚检,大力开展梅毒筛查以及加强流动人口的管理,对预防先天性梅毒的发生很有必要.
目的 為瞭解3箇月以下幼嬰先天性梅毒(CS)的臨床特點及誤診情況.方法 收集我院1997年1月-2007年5月確診為先天性梅毒的3箇月以下幼嬰121例,將臨床錶現、實驗室檢查及治療情況進行迴顧性分析.結果 3箇月以下幼嬰先天性梅毒的臨床錶現多樣,纍及皮膚、呼吸、消化、血液、神經、骨骼等多繫統,121例中白細胞增高89.3%,皮膚損害59.5%,肝髒腫大56.2%,脾腫大41.3%,貧血38.8%,髮熱28.9%,病理性黃疸24.0%,齣生後生長髮育遲緩12.4%,骨骼損害54.3%等;誤診率17.4%,誤診疾病達10種.結論 3箇月以下幼嬰先天性梅毒的臨床錶現複雜多變,缺乏特異性,易被誤診,需要臨床醫師提高警惕;恢複婚檢,大力開展梅毒篩查以及加彊流動人口的管理,對預防先天性梅毒的髮生很有必要.
목적 위료해3개월이하유영선천성매독(CS)적림상특점급오진정황.방법 수집아원1997년1월-2007년5월학진위선천성매독적3개월이하유영121례,장림상표현、실험실검사급치료정황진행회고성분석.결과 3개월이하유영선천성매독적림상표현다양,루급피부、호흡、소화、혈액、신경、골격등다계통,121례중백세포증고89.3%,피부손해59.5%,간장종대56.2%,비종대41.3%,빈혈38.8%,발열28.9%,병이성황달24.0%,출생후생장발육지완12.4%,골격손해54.3%등;오진솔17.4%,오진질병체10충.결론 3개월이하유영선천성매독적림상표현복잡다변,결핍특이성,역피오진,수요림상의사제고경척;회복혼검,대력개전매독사사이급가강류동인구적관리,대예방선천성매독적발생흔유필요.
Objective To investigate the clinical features and diagnosis of infants under 3 months of age with congenital syphilis. Method Data of 121 infants below 3 months of age with congenital syphilis were collected from January 1997 to May 2007 at the authors' hospital. Their clinical features, laboratory findings and treatment were reviewed. Result Clinical manifestations of congenital syphilis in the infants were diverse. The disease involved multiple systems such as the skin, respiratory, digestive, blood, and nervous system, skeleton and so on. Among the 121 infants,the manifestations included increased leukocyte count (89.3%), skin damage (59.5%), hepatomegaly (56.2%), splenomegaly (41.3%), anemia (38.8%), fever (28.9%), pathologic jaundice (24.0%), growth retardation after birth (12.4%) and bone damage (54.3%), etc. The rate of misdiagnosis was 17.4 percent, and the kinds of disease misdiagnosed were up to 10. Conclusion Clinical manifestations of congenital syphilis in infants under 3 months of age were complicated and nonspecifie, therefore doctors misdiagnosed it very easily. Clinicians should attach great importance to it. At the same time, the restoration of antemarital examination, vigorously carrying out screening for syphilis and strengthening the management of immigrants are necessary to prevent congenital syphilis.
